Purdue vs Notre Dame Prediction Football Picks Today 9/26/26

The Notre Dame Fighting Irish and the Purdue Boilermakers meet in week 4 college football action from Ross Ade Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Notre Dame Fighting Irish vs. Purdue Boilermakers Prediction.

Notre Dame Fighting Irish Recap

The Notre Dame Fighting Irish come into this game looking to add on to a 27-10 win over Michigan State last time out to sit at 3-0 this season. After this game, Notre Dame will head on the road for a game against North Carolina.

Irish Looking To Stay Undefeated

CJ Carr has thrown for 726 yards, 6 touchdowns and 0 interceptions on 72.6% passing while Nolan James Jr. leads Notre Dame in rushing with 169 rushing yards and 3 touchdowns so far this season. Aneyas Williams sits behind James Jr. on the ground with 144 yards and 3 TDs. Micah Gilbert leads the Fighting Irish in receiving with 251 yards on 13 catches along with 1 touchdown, while Jordan Faison trails with 173 yards on 13 catches along with 2 touchdowns. On defense, Drayk Bowen has a team-high 19 total tackles, Boubacar Traore leads the team with 2 sacks, and Adon Shuler, Luke Talich, and Madden Faraimo have each recorded 1 interception. Notre Dame’s defense as a whole has combined for 7 sacks and 3 interceptions so far this season.

Purdue Boilermakers Recap

The Purdue Boilermakers come into this game looking to bounce back from a 52-38 loss at the hands of the UCLA Bruins last time out to sit at 1-2 this season. After this game, Purdue will head on the road for a game against Illinois.

Boilermakers Drop Back-To-Back Games

Ryan Browne has thrown for 1,024 yards, 7 touchdowns and 1 interception on 73.3% passing while Fame Ijeboi leads Purdue in rushing with 248 rushing yards and 0 touchdowns so far this season. Travis Terrell Jr. sits behind Ijeboi on the ground with 43 yards and 0 TDs. Arzaad Waseem leads the Boilermakers in receiving with 321 yards on 20 catches along with 1 touchdown, while Xavier Townsend trails with 141 yards on 10 catches along with 2 touchdowns. On defense, John Slaughter has a team-high 22 total tackles, Demetrius Saunders has recorded 1 interception, and Purdue’s defense as a whole has combined for 6 sacks and 1 interception so far this season.

Notre Dame Fighting Irish @ Purdue Boilermakers Betting Trends: Week 4

Why the Purdue Boilermakers will win

• Purdue has won six of its last eight home games against teams from Indiana.
• The underdog has covered the spread in four of Purdue’s last five games at Ross-Ade Stadium.
• Notre Dame has failed to cover the spread in three of its last four road games as a top-15 AP-ranked team.
• The home team has won the first quarter in seven of Purdue’s last nine games.
• Purdue has won the first half in three of its last four home games against non-conference opponents.

Why the Notre Dame Fighting Irish will win

• Notre Dame has won each of its last 18 games against non-AP-ranked teams.
• Purdue has lost each of its last 15 games against AP-ranked teams.
• Purdue has failed to cover the spread in each of its last five games as an underdog against teams from Indiana.
• Notre Dame has covered the spread in each of its last four games against teams from Indiana.
• Notre Dame has won the first quarter in each of its last nine games as a top-10 AP-ranked team against a non-AP-ranked team.
• Purdue has lost the first half in each of its last 15 games against AP-ranked teams.

Total Points Facts

• Ten of Notre Dame’s last 11 September road games against non-AP-ranked teams have gone OVER the total points line.
• Each of Purdue’s last five games have gone OVER the total points line.

Purdue Boilermakers Player Prop Facts

• Ryan Browne has recorded 300+ passing yards in three consecutive games – equal-longest streak in the FBS, heading into Week 4.

Notre Dame Fighting Irish Player Prop Facts

• Heading into Week 4, Nolan James Jr. ranks T1st amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

• Purdue ranks 3rd among FBS teams for passing yards per game this season (366.7).
• Purdue ranks T130th among FBS teams for 4th down conversion percentage against this season (100.0).
• Notre Dame ranks T1st among FBS teams for Q4 opponent points per game this season (0.0).
• Notre Dame ranks T1st among FBS teams for H2 opponent points per game this season (1.0).

Notre Dame Fighting Irish vs. Purdue Boilermakers Prediction

I’m on Purdue here. I get the case to be made for Notre Dame as the Irish historically have demolished Purdue with no regard for the Boilermakers. That being said, Purdue’s got something offensively here and this is a boatload of points for a Purdue team that went shot for shot with UCLA last week against a Notre Dame team that clearly doesn’t have the same punch as last season. Give me Purdue and the points.