Reds vs Blue Jays Prediction 9/26/26 MLB Picks Today

In this article, we will formulate a Reds vs Blue Jays Prediction for this MLB matchup on Saturday, September 26^th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Toronto Blue Jays Preview

The Toronto Blue Jays have a 78-82 record this season and are sitting in the 5th place of the AL East. They have a 41-38 home record and are coming off a 6-5 home win against the Reds.

The Toronto Blue Jays have a .248 batting average this season, .311 OBP and .382 Slugging percentage. Toronto’s pitching staff has a 3.92 ERA and 1.30 WHIP. Vladimir Guerrero Jr. is the team’s best hitter with a .262 batting average. Kazuma Okamoto leads the team in RBI with 92, adding a team-high 33 home runs.

Trey Yesavage (R) is the projected starting pitcher for the Blue Jays, and he has a 5-5 record, 3.67 ERA and 1.13 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 74-86 record this season and are sitting in the 5th place of the NL Central. They have a 36-43 away record and are coming off a 5-6 road loss against the Blue Jays.

The Cincinnati Reds have a .229 batting average this season, .305 OBP and .395 Slugging percentage. Cincinnati’s pitching staff has a 4.85 ERA and 1.45 WHIP. Elly De La Cruz is the team’s best hitter with a .285 batting average. Sal Stewart leads the team in RBI with 111, adding a team-high 32 home runs.

Rhett Lowder (R) is the projected starting pitcher for the Reds, and he has a 6-12 record, 6.01 ERA and 1.55 WHIP.

Cincinnati Reds @ Toronto Blue Jays Betting Trends: September 26, 2026

• Probable Starting Pitcher: Trey Yesavage      Record this season: 5-5      ERA: 3.67
• Home Record: 3-3
• Last 5 against Reds: –

Why the Toronto Blue Jays will win

• The home team has won seven of the Blue Jays’ last eight games.
• The Reds have lost each of their last five road games against AL opponents that held a losing record.
• The Reds have failed to cover the run line in nine of their last 11 games against teams that held a losing record.
• The Blue Jays have covered the run line in each of their last three games against NL opponents after playing the previous day.
• The Reds have lost the first inning in each of their last four games at Rogers Centre.
• The Reds have trailed after 3 innings in each of their last three day games.
• The Blue Jays have led after 5 innings in each of their last four home day games.

• Probable Starting Pitcher: Rhett Lowder      Record this season: 6-12      ERA: 6.01
• Road Record: 4-8
• Last 5 against Blue Jays: –

Why the Cincinnati Reds will win

• The Reds have won each of their last six games as underdogs against AL opponents following a loss.
• The Blue Jays have lost five of their last six games as favorites following a win.
• The road team has covered the run line in each of the Reds’ last six games.
• The Blue Jays have failed to cover the run line in eight of their last nine games as favorites following a win.
• The Blue Jays have trailed after 3 innings in five of their last six games against opponents that held a losing record.
• The Reds have led after 5 innings in each of their last four day games against AL opponents that held a losing record.

Total Runs Facts

• Each of the last eight games between the Reds and Blue Jays have gone OVER the total runs line.
• Each of the Reds’ last six games as underdogs against the Blue Jays have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Reds’ last five games at Rogers Centre.
• There has been at least one run scored in the first inning in five of the Blue Jays’ last six games.

Toronto Blue Jays Player Prop Facts

• George Springer has hit at least one home run in three of the Blue Jays’ last four games as favorites against the Reds.
• Trey Yesavage has recorded four or more strikeouts in each of his last 10 appearances in day games.
• George Springer has recorded at least one hit in each of his last eight appearances against the Reds after playing the previous day.

Cincinnati Reds Player Prop Facts

• Eugenio Suarez has hit a home run in four of his last five road appearances against AL opponents.
• Rhett Lowder has recorded four or more strikeouts in seven of his last eight appearances with the Reds as road underdogs.
• Tyler Stephenson has recorded at least one hit in each of his last 10 appearances in day games against teams that held a losing record.
• Elly De La Cruz ranks 8th amongst qualified players for Slugging Percentage (.521) this season.

Matchup/League Facts

• The Blue Jays rank 30th in the league for runs scored this season (642).
• The Blue Jays rank 30th in the league for home runs this season (150).
• The Reds rank 30th in the league for hits this season (1218).
• The Reds rank 30th in the league for batting average this season (.229).

Reds vs Blue Jays Prediction

The Blue Jays are 6-3 in their last 9 meetings against the Reds and have won two of their last three meetings in Toronto.

In this Reds vs Blue Jays Prediction, the Blue Jays are coming as -160 home favorites. I like the Jays in this one as they have the pitching edge with Trey Yesavage going up against Rhett Lowder. Yesavage has just two earned runs in his last three starts, while Lowder has been atrocious on the road with a 4-8 record and 7.44 ERA. On top of that, during their last 5 games, the Jays have a better offense and a 1.88 bullpen ERA. Take the Jays to win this one.