Seattle Seahawks vs LA Chargers Prediction 10/4/26 NFL Picks Today
LA Chargers (0-3) vs. Seattle Seahawks (2-1)
October 4, 2026 4:25 pm EDT
The Line: Seattle Seahawks -6.5; Over/Under: 43.5
(Get latest betting odds)
The Los Angeles Chargers and the Seattle Seahawks meet Sunday in NFL action from Lumen Field in Seattle. Here’s a Seahawks vs Chargers prediction. We will look at this from a betting perspective and determine the best Seahawks vs Chargers pick.
Los Angeles Chargers Betting Preview
Los Angeles had a manageable matchup versus the Arizona Cardinals at home in their opener this year. The Chargers were outscored 10-0 in the fourth quarter though, and lost that one 26-14. In game two it was another winnable home game versus the Las Vegas Raiders. LA was outscored 9-0 in the fourth quarter this time, leading to a 26-14 defeat for an 0-2 start.
Last weekend versus the Bills, the Chargers were up 10-0 by the end of the first quarter but saw that lead evaporate by halftime. LA got a couple of field goals after that but it wasn’t enough in a 24-16 road loss. QB Justin Herbert was 20-of-34 for 226 yards, one TD and one pick. Tre Harris put up six receptions for 76 yards as the leading receiver in the defeat.
Seattle Seahawks Betting Preview
Over on the Seahawks’ side, they kicked off the year with a tough matchup versus the New England Patriots. Seattle surged on a 10-0 fourth-quarter run, ultimately pulling out the win 13-10. In game two versus the Arizona Cardinals, the Seahawks kept it going. Seattle posted a 24-0 advantage in the second half on the way to a 31-7 road victory.
Matched up against the Washington Commanders in game three, the Seahawks were within seven points 17-10 by the end of the first half. Seattle traded touchdowns in the third and had a 14-9 advantage in the fourth but came up short 33-31 in the end. Sam Darnold was 31-of-45 for 379 yards, four scores and two interceptions. Jaxon Smith-Njigba had 10 catches for 128 yards and two scores.
Los Angeles Chargers @ Seattle Seahawks Betting Trends: Week 4
Why the Seattle Seahawks will win
- The Seahawks have won each of their last nine games played on the West Coast.
- The Chargers have lost each of their last six games.
- The Chargers have failed to cover the spread in each of their last six games.
- The Seahawks have covered the spread in each of their last four home games against teams that held a losing record.
- The Seahawks have won the first quarter in each of their last six Week 4 games as favorites.
- The Seahawks have won the first half in each of their last five home games against teams that held a losing record.
- The Seahawks have scored the first touchdown in each of their last seven home games against AFC West opponents.
Why the Los Angeles Chargers will win
- The Chargers have won each of their last three games as underdogs against NFC opponents.
- The Seahawks have lost six of their last nine games as home favorites following a loss.
- The Chargers have covered the spread in each of their last nine games as road underdogs against NFC opponents.
- The Seahawks have failed to cover the spread in seven of their last eight games as favorites without Uchenna Nwosu.
- The Chargers have scored the first touchdown in each of their last four games played as underdogs on the West Coast.
- The Chargers have won the first quarter in six of their last eight games as underdogs against reigning Super Bowl champions.
- The Chargers have won the first half in each of their last seven games as road underdogs against NFC opponents.
Total Points Facts
- Each of the Chargers’ last six games have gone UNDER the total points line.
- Each of the Seahawks’ last five Week 4 games as favorites have gone UNDER the total points line.
Seattle Seahawks Player Prop Facts
- Jaxon Smith-Njigba has scored a touchdown in each of the Seahawks’ last six October games as favorites.
- Cooper Kupp has recorded 24+ receiving yards in each of his last 26 appearances against AFC opponents.
- Zach Charbonnet has scored the first touchdown in each of his last three regular season appearances with the Seahawks as favorites.
- Jaxon Smith-Njigba has scored two touchdowns in three of the Seahawks’ last four games against teams that held a losing record.
- Drew Lock has recorded 10+ rushing yards in four of his last five appearances against AFC opponents.
- Sam Darnold has recorded 240+ passing yards in each of his last six appearances following a loss.
- Cooper Kupp has recorded 24+ rushing and receiving yards in each of his last 26 appearances against AFC opponents.
- Drew Lock has recorded 19+ completions in seven of his last eight appearances as a starter.
- Heading into Week 4, Jaxon Smith-Njigba ranks 1st in the NFL in receiving yards (405) this season.
Los Angeles Chargers Player Prop Facts
- Omarion Hampton has scored a touchdown in each of the Chargers’ last four games played on the West Coast.
- Justin Herbert has recorded 24+ rushing yards in each of the Chargers’ last six games against NFC opponents.
- Justin Herbert has recorded 242+ passing yards in each of his last five road appearances on the West Coast.
- Quentin Johnston has recorded 40+ rushing and receiving yards in eight of his last nine regular season road appearances.
- Quentin Johnston has recorded 40+ receiving yards in eight of his last nine regular season road appearances.
- Justin Herbert has recorded 21+ completions in six of the Chargers’ last seven October road games.
- Heading into Week 4, Genesis Smith has recorded the equal-most interceptions in a single game this season (2 vs Bills, Week 3).
Matchup/League Facts
- Heading into Week 4, the Seahawks rank 1st in the NFL in yards allowed per game (228.7) this season.
- Heading into Week 4, the Seahawks rank 1st in the NFL in passing yards allowed per game (141.7) this season.
- Heading into Week 4, the Chargers rank 32nd in the NFL in Q4 points per game (1.0) this season.
- Heading into Week 4, the Chargers rank T1st in the NFL in Q3 win percentage (66.7) this season.
Seahawks vs Chargers Prediction
I’ll go with the Seahawks. Seattle shot themselves in the proverbial foot several times in their two-point road loss to the Commanders last weekend. The Seahawks posted 393 pass yards and 28 first downs but went just 3-of-9 on third-downs along with three turnovers. The eight penalties for 53 yards didn’t help either. The defense actually played quite well with 17 first downs and 3-of-13 on third downs allowed. It was a weird statistical game.
As for LA, they couldn’t get a whole lot going versus the Bills last weekend, with 348 yards, 20 first downs and 6-of-15 on third-down tries in the books. The Chargers defense came up with five takeaways and the team benefitted from 10 Buffalo penalties but it wasn’t enough. This week’s matchup will be another tricky one, and it’ll be a fun game to watch.

