Washington Huskies (3-1) vs. USC Trojans (4-1)
October 3, 2026 7:30 pm EDT
The Line: USC Trojans -9.5 / Washington Huskies 9.5; Over/Under: 58.5
(Get latest betting odds)
The Washington Huskies and USC Trojans meet Saturday in week 5 college football action at Los Angeles Memorial Coliseum. Here’s a USC vs. Washington Prediction. This article will include a USC vs. Washington Pick.
Washington Huskies Betting Preview
The Washington Huskies beat Eastern Washington, lost to Minnesota, and they play Iowa next. The Washington Huskies have won 12 of their last 17 games. Demond Williams Jr. is completing 69.3 percent of his passes for 1,129 yards, 7 touchdowns, and 3 interceptions. Dezman Roebuck and Chris Lawson have combined for 520 receiving yards and 2 touchdowns, while Baron Naone has 13 receptions.
The Washington Huskies’ ground game is averaging 107.3 yards per contest, and Demond Williams Jr. leads the way with 165 yards and 2 touchdowns. Defensively, Washington is allowing 16.8 points and 289.3 yards per game. Alex McLaughlin leads the Washington Huskies with 24 tackles, Jacob Manu has 2 sacks, and Dylan Robinson has 1 interception.
USC Trojans Betting Preview
The USC Trojans beat Rutgers, lost to Oregon, and they play Penn State next. The USC Trojans have won 13 of their last 18 games. Jayden Maiava is completing 70.1 percent of his passes for 1,499 yards, 14 touchdowns, and 2 interceptions. Kayden Dixon-Wyatt and Trent Mosley have combined for 627 receiving yards and 7 touchdowns, while Mark Bowman has 21 receptions.
The USC Trojans’ ground game is averaging 164.4 yards per contest, and King Miller leads the way with 412 yards and 3 touchdowns. Defensively, USC is allowing 26.4 points and 354.8 yards per game. Deven Bryant leads the USC Trojans with 27 tackles, Jadyn Ramos has 2 sacks, and Prophet Brown has 2 interceptions.
Why the USC Trojans will win
- USC has won each of its last 19 home games as an AP-ranked team against a non-AP-ranked team.
- Washington has lost each of its last six games as an underdog against AP-ranked teams.
- Washington has failed to cover the spread in each of its last seven road games in October.
- USC has covered the spread in four of its last five games in October.
- USC has won the first quarter in each of its last six games against non-AP-ranked teams.
- Washington has lost the first half in each of its last six games as an underdog against AP-ranked teams.
Why the Washington Huskies will win
- Washington has won each of its last eight games against teams from California.
- USC has lost four of its last five October games as an AP-ranked team.
- USC has failed to cover the spread in eight of its last nine games.
- Washington has covered the spread in each of its last five games against teams from California.
- Washington has won the first half in each of its last eight games against teams from California.
- Washington has won the first quarter in seven of its last eight games against teams from California.
Total Points Facts
- Seven of Washington’s last eight games as an underdog against teams from California have gone UNDER the total points line.
- Each of USC’s last four games as a favorite against teams from Washington have gone UNDER the total points line.
USC Trojans Player Prop Facts
- Heading into Week 5, Jayden Maiava ranks 1st amongst FBS players for passing yards (1499) this season.
Washington Huskies Player Prop Facts
- Dezmen Roebuck has recorded 7+ receptions in four consecutive games- the longest streak in the FBS, heading into Week 5.
Matchup/League Facts
- USC has recorded the equal-most home wins by a margin of 10+ points of any FBS team this season (3).
- USC has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (3).
- Two of Washington’s four games this season have been decided by a margin of three points or less – equal-most amongst FBS teams.
- Washington ranks T5th among FBS teams for interceptions this season (6).
USC vs Washington Prediction
USC and Washington are a combined 1-8 ATS on the season, so there’s that. USC has failed to cover 8 of its last 9 games, while Washington is 1-5 ATS in its last 6 games. I’m still grabbing the points with Washington. The Huskies have the defense to give USC problems, especially with its inability to run the ball consistently. Washington also has a playmaker at quarterback, and that USC pass defense is 106th in the country. If there was a game for Williams to go crazy and get this Washington offense in gear, it’s probably this one. This feels like a back-and-forth, high-scoring game. Give me the points.
