St. Louis Blues vs Vegas Golden Knights Prediction 10/22/26 NHL Picks Today
Vegas Golden Knights (8-3) vs. St. Louis Blues (4-4)
October 22, 2026 8:00 pm EDT
The Line: St. Louis Blues +105 / Vegas Golden Knights -125; Over/Under: 6.5
(Get latest betting odds)
The Vegas Golden Knights and the St. Louis Blues meet Thursday in NHL action from the Enterprise Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Vegas Golden Knights vs. St. Louis Blues prediction.
Vegas Golden Knights Recap
The Vegas Golden Knights come into this game looking to bounce back from a 6-2 loss at the hands of Tampa Bay last time out to sit at 8-3 this season. After this game, the Golden Knights will head on the road for a game against the Columbus Blue Jackets.
Golden Knights Have Three-Game Win Streak Snapped
Jack Eichel leads the Vegas Golden Knights through eleven games this season with a team-high 18 points, totaling 5 goals and a team-leading 13 assists. Mark Stone sits in second with 15 points, leading the squad with 8 goals alongside 7 assists, while Mitch Marner records 12 points with 2 goals and 10 assists. Ivan Barbashev adds 8 points with a goal and 7 assists, while Tomas Hertl, Trevor Connelly, and Brett Howden occupy the next tier with 7 points apiece, each contributing 4 goals and 3 assists. Brayden McNabb chips in 6 points on 6 assists, while William Karlsson, Victor Olofsson, Rasmus Andersson, Braeden Bowman, Noah Hanifin, and Shea Theodore round out Vegas’s primary contributors with 4 to 5 points each. In net, Carter Hart holds a 4-3-0 record with a 2.87 GAA and an .888 save percentage after stopping 158 of 178 shots, while Adin Hill posts a 4-0-0 mark with a 2.21 GAA and a .906 save percentage after stopping 87 of 96 shots for the Golden Knights up to this point in the season.
St. Louis Blues Recap
The St. Louis Blues come into this game looking to add on to their 2-1 win over Winnipeg last time out to sit at 4-4-1 this season. After this game, the Blues will take on the Carolina Hurricanes in a matchup at home.
Blues Snap Two-Game Slide
Mason McTavish leads the St. Louis Blues through nine games this season with a team-high 9 points, totaling a team-leading 5 goals and 4 assists. Dylan Holloway sits in second with 7 points on a goal and a team-leading 6 assists, while Jimmy Snuggerud, Pius Suter, Philip Broberg, and Connor McMichael occupy the next tier with 6 points apiece, with Snuggerud potting 5 goals, Suter adding 3 goals and 3 assists, Broberg recording 2 goals and 4 assists, and McMichael chipping in 2 goals and 4 assists. Pavel Buchnevich, Robert Thomas, and Jake Neighbours record 5 points each, with Neighbours scoring 3 goals, while Colton Parayko, Jonatan Berggren, Cam Fowler, and Dalibor Dvorsky round out St. Louis’s primary contributors with 3 to 4 points each. In net, Joel Hofer holds a 3-2-1 record with a 2.20 GAA and a .919 save percentage after stopping 148 of 161 shots, while Jordan Binnington posts a 1-2-0 mark with a 4.68 GAA and an .831 save percentage after stopping 69 of 83 shots for the Blues up to this point in the season.
Vegas Golden Knights vs. St. Louis Blues Prediction
I’m on the Golden Knights in this one. I get the case to be made for either side in this game as Vegas has been a different team outside of Sin City. However, I still think the Golden Knights are the better team and they’ve also owned the head-to-head against St. Louis recently, winning 6 of the last 8 meetings between these two teams.