College Football

Houston vs Colorado Prediction Football Picks Today 11/13/26

Houston Cougars (7-2) vs. Colorado Buffaloes (3-6)
November 13, 2026 10:15 pm EDT
The Line: Colorado Buffaloes 310 / Houston Cougars -395; Over/Under: 50.5
(Get latest betting odds)

Houston vs Colorado Prediction

In this Houston vs Colorado prediction for this College Football Week 11 matchup on Friday, November 13th, Houston is coming as -10.5 road favorites. Houston has been the far better team this season with a better record and in far better form, with a 5-1 in their last 6 games but just 1-5 against the spread in its last 6. On the flip side, Colorado has been struggling mightily with a 1-6 record in its last 7 games and 1-7 against the spread in its last 8, being inferior both on the offensive and the defensive end, with a -8.5 point differential, as opposed to Houston’s +14.1. Houston almost cracks the top-40 of the entire country both offensively and defensively and I expect them to get the job done comfortably on the road today. Take Houston and lay the -10.5 points.

Colorado Buffaloes Preview

Colorado has a 3-6 record and a 1-5 record in the Big 12. They are coming off a 10-20 road loss against Arizona State and will face Cincinnati and UCF next.

Offensively, Colorado averages 19.8 points per game, ranking 124th in the nation, while defensively, they allow 28.3 points per game, which is 101st. Colorado averages 385.7 total yards per game (255.4 passing and 130.2 rushing), while allowing 376.9 total yards per game (133.2 rushing and 243.7 passing). They average 68.7 plays per game and 5.6 yards per play on offense, while allowing 70.4 plays per game and 5.4 yards per play on defense. Colorado averages 20 first downs per game on offense and 21.1 first downs per game on defense. They are averaging 2 turnovers per game and forcing 0.8 turnovers per game.

Isaac Wilson leads Colorado with 1,412 passing yards with 61.7% completed passes and 8 touchdowns. JaQuail Smith leads the team in rushing yards with 384, while Joseph Williams has a team-high 853 receiving yards and 58 receptions. Defensively, Gideon Lampron has a team-high 99 total tackles (53 of them solo) and leads the team with 5.5 sacks.

Houston Cougars Preview

Houston has a 7-2 record and a 4-2 record in the Big 12. They are coming off a 31-24 home win against Cincinnati and will face West Virginia and Baylor next.

Offensively, Houston averages 35.4 points per game, ranking 22nd in the nation, while defensively, they allow 21.3 points per game, which is 41st. Houston averages 470.2 total yards per game (262.6 passing and 207.7 rushing), while allowing 360.2 total yards per game (107.3 rushing and 252.9 passing). They average 69.1 plays per game and 6.8 yards per play on offense, while allowing 61 plays per game and 5.9 yards per play on defense. Houston averages 25.3 first downs per game on offense and 19.9 first downs per game on defense. They are averaging 0.7 turnovers per game and forcing 1.4 turnovers per game.

Conner Weigman leads Houston with 2,280 passing yards with 66.1% completed passes and 22 touchdowns, and he leads the team in rushing yards with 279. Amare Thomas has a team-high 698 receiving yards and 47 receptions. Defensively, Kentrell Webb has a team-high 50 total tackles (40 of them solo), while Ashton Porter leads the team with 3 sacks.

Houston Cougars @ Colorado Buffaloes Betting Trends: Week 11

 

Why the Colorado Buffaloes will win

  • Houston has lost three of its last four November games as a favorite against non-AP-ranked teams.
  • The home team has won each of Houston’s last three games.
  • Houston has failed to cover the spread in each of its last six November games as a favorite against non-AP-ranked teams.
  • Colorado has covered the spread in seven of its last eight games against AP-ranked teams at Folsom Field.

Why the Houston Cougars will win

  • Colorado has lost each of its last 14 November games as an underdog.
  • Houston has won each of its last seven road games against non-AP-ranked teams.
  • Colorado has failed to cover the spread in each of its last four games against teams from Texas.
  • Houston has covered the spread in six of its last seven road games in November.
  • Colorado has lost the first half in 12 of its last 14 November games as an underdog.

Total Points Facts

  • Ten of Houston’s last 12 games as a favorite have gone OVER the total points line.
  • Five of Colorado’s last six games at Folsom Field have gone OVER the total points line.

Colorado Buffaloes Player Prop Facts

  • Heading into Week 11, Joseph Williams leads Colorado for receptions (58) this season.

Houston Cougars Player Prop Facts

  • Heading into Week 11, Conner Weigman ranks 8th amongst FBS players for passing touchdowns (22) this season.

Matchup/League Facts

  • Colorado ranks 132nd among FBS teams for average point differential in second quarters this season (-5.1).
  • Colorado ranks T126th among FBS teams for Q4 points per game this season (4.7).
  • Houston ranks T7th among FBS teams for Q1 opponent points per game this season (2.2).
  • Houston ranks 7th among FBS teams for H1 opponent points per game this season (6.8).

Nikos Lagouretos's Free Pick: Houston -10.5

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