Panthers vs Saints Prediction 11/15/26 NFL Picks Today

Panthers vs Saints Prediction

In this Panthers vs Saints prediction, New Orleans is coming in as a -2.5 favorite at home. The two teams have the exact same record this season and neither one has looked good lately. New Orleans has gone 2-4 over its last 6 games and 1-5 against the spread in that stretch, and it has only one home win all season. Carolina has lost three in a row without covering in any of them and even though its offense has been better than New Orleans’ overall, it is scoring just 17.6 points per game over those last three. The history is not on Carolina’s side either, it is 1-5 in the last 6 meetings between the two and it lost each of its last three trips to New Orleans. I’m taking New Orleans and laying the small number in this one.

New Orleans Saints Preview

New Orleans is 3-5 this season and sits in 1st place in the NFC South. It has gone 1-4 at home and 2-1 on the road, with a 3-5 record against the spread and a 5-3 record on the over/under. New Orleans won Cleveland 23-22 at home in its last game, and Chicago and Cincinnati are next.

New Orleans scores 23.1 points per game, 15th in the NFL, and gives up 27, which ranks 27th. The offense is gaining 325.8 total yards per game, 230.5 through the air and 95.3 on the ground. The defense allows 370.5 yards per game, with 236.6 passing and 133.9 rushing. On a per-play basis, New Orleans gains 4.9 yards and allows 5.7. It scores on 37.2% of its drives for 2.09 points per drive, while opponents score on 45.6% of theirs and average 2.43 points per drive. New Orleans has given the ball away 15 times and taken it away 9 times, leaving its turnover margin at -6.

Tyler Shough has thrown for 1986 yards and fourteen touchdowns while completing 66.2% of his passes. He is also the team’s leading rusher with 162 yards. Chris Olave has 56 catches for a team-high 734 receiving yards. On defense, Pete Werner leads the team with 65 total tackles, 29 of them solo, and Chase Young has a team-best 8 sacks.

Injury Report:

• Taliese Fuaga (Questionable, Knee) – Est. return Nov 15
• David Edwards (Questionable, Knee) – Est. return Nov 15
• Kelvin Banks Jr. (Questionable, Ankle) – Est. return Nov 15
• Quincy Riley (Questionable, Knee) – Est. return Nov 15
• CJ Donaldson (Questionable, Shoulder) – Est. return Nov 15

Carolina Panthers Preview

Carolina is 3-5 as well and sits in 1st place in the NFC South. It is 1-3 at home and 2-2 on the road, 3-5 against the spread and 4-4 on the over/under. Carolina lost 21-26 at home to Denver in its last game and has Baltimore and Tampa Bay coming up.

Carolina averages 24.9 points per game, which ranks 11th in the NFL, but it allows 27.4, 28th in the league. The offense produces 362.4 total yards per game, with 261.1 passing and 101.3 rushing. Opponents are gaining 344.9 yards per game against Carolina, 211.5 through the air and 133.4 on the ground. Carolina averages 5.5 yards per play and gives up 5.3. It has scored on 40.4% of its drives and averages 2.25 points per drive, while its defense has allowed scores on 41.1% of drives and 2.34 points per drive. Carolina has 12 giveaways and 11 takeaways, so its turnover margin is -1.

Bryce Young leads Carolina with 2197 passing yards, a 60.4% completion rate and sixteen touchdowns. Chuba Hubbard is the top rusher with 619 yards, and Tetairoa McMillan leads the receivers with 46 catches for 625 yards. On the defensive side, Devin Lloyd has a team-high 54 total tackles, 32 of them solo, and Princely Umanmielen leads the team with 3 sacks.

Injury Report:

• Xavier Legette (IR-R, Knee) – Est. return Nov 15
• Jonathon Brooks (IR-R, Groin) – Est. return Nov 15
• Bobby Okereke (Questionable, Foot) – Est. return Nov 15
• Mike Jackson (IR-R, Groin) – Est. return Nov 15
• Jaycee Horn (IR, Quadriceps) – Est. return Nov 15

Carolina Panthers @ New Orleans Saints Betting Trends: Week 10

Why the New Orleans Saints will win

• The Saints have won seven of their last eight home games against opponents on a losing streak.
• The Panthers have lost each of their last four road games without Jalen Coker.
• The Saints have covered the spread in seven of their last eight games without Julian Blackmon.
• The Panthers have failed to cover the spread in four of their last five games without Bryce Young.
• The Saints have won the first half in each of their last four home games following an overtime win.
• The Saints have won the first quarter in three of their last four games after coming off overtime.

Why the Carolina Panthers will win

• The Saints have lost each of their last four November games as favorites against NFC South opponents.
• The Panthers have won four of their last five games as underdogs against NFC South opponents.
• The Panthers have covered the spread in seven of their last eight games as underdogs against NFC South opponents.
• The Saints have failed to cover the spread in seven of their last eight November games as favorites.
• The Saints have lost the first quarter in each of their last four games as favorites against NFC opponents.
• The Panthers have won the first half in each of their last four Week 10 games as underdogs.

Total Points Facts

• Each of the Panthers’ last six road games against NFC opponents have gone UNDER the total points line.
• Each of the Saints’ last five games as favorites have gone OVER the total points line.
• Eleven of the last 14 Sunday day games at Caesars Superdome have gone UNDER the total points line.

New Orleans Saints Player Prop Facts

• Audric Estime has scored a touchdown in three of his last four appearances.
• Tyler Shough has recorded 22+ rushing yards in four of the Saints’ last five games against NFC South opponents.
• Juwan Johnson has recorded 26+ receiving yards in seven of the Saints’ last eight games as favorites following a win.
• Tyler Shough has recorded 255+ passing yards in each of the Saints’ last four games as home favorites.
• Tyler Shough has recorded 29+ completions in three of the Saints’ last four Sunday games as home favorites.
• Audric Estime has recorded 77+ rushing and receiving yards in three of his last four appearances.
• Heading into Week 10, Tyler Shough ranks 1st in the league for times blitzed (112) this season.

Carolina Panthers Player Prop Facts

• Tetairoa McMillan has scored the last touchdown in each of the Panthers’ last four November games as underdogs.
• Tetairoa McMillan has scored at least one touchdown in each of the Panthers’ last four November games.
• Bryce Young has recorded 266+ passing yards in each of the Panthers’ last four day road games.
• Bryce Young has recorded 23+ completions in each of the Panthers’ last five games following a loss.
• AJ Dillon has recorded 10+ receiving yards in each of his six previous November road appearances.
• AJ Dillon has recorded 14+ rushing yards in each of his 14 previous appearances in Sunday day games with his team as an underdog.
• AJ Dillon has recorded 28+ rushing and receiving yards in each of his last 13 appearances in Sunday day games with his team as an underdog.
• Heading into Week 10, Jalen Coker ranks T3rd in the NFC for 20+ yard receiving touchdowns (2) this season.

Matchup/League Facts

• Heading into Week 10, the Saints rank 32nd in the NFL in Q1 points per game (1.1) this season.
• Heading into Week 10, the Saints rank 32nd in the NFL in average points scored in first quarters this season (1.1).
• Heading into Week 10, the Panthers have recorded the largest margin of victory in a road game this season (31-points vs Atlanta on September 20, 2026).
• Heading into Week 10, the Panthers have conceded the highest score in a single game this season (59-points vs Chicago).