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Stampeders vs Lions Prediction 9-19-25 CFL Picks

Stampeders vs Lions
September 19, 2025 9:30 pm EDT
The Line: Lions +5
(Get latest betting odds)

The BC Lions and Calgary Stampeders meet Friday in CFL action at McMahon Stadium. Here’s a Stampeders vs Lions Prediction. This article will include a Stampeders vs Lions Pick.

BC Lions Betting Preview

The BC Lions lost to the Redblacks, beat the Redblacks, and they play the Argonauts next. The BC Lions have lost 4 of their last 7 games. Nathan Rourke is completing 68.6 percent of his passes for 3,604 yards, 20 touchdowns and 9 interceptions. Keon Hatcher and Justin Mcinnis have combined for 2,058 receiving yards and 8 touchdowns, while Ayden Eberhardt has 36 receptions.

The BC Lions ground game is averaging 108 yards per contest, and James Butler leads the way with 989 yards and 10 touchdowns. Defensively, BC is allowing 29.6 points and 373.6 yards per game. Micah Awe leads the BC Lions with 96 tackles, Mathieu Betts has 8 sacks and Garry Peters has 2 interceptions.

Calgary Stampeders Betting Preview

The Calgary Stampeders beat the Elks, lost to the Elks, and they play the Alouettes next. The Stampeders have won 6 of their last 9 games. Vernon Adams Jr. is completing 64.6 percent of his passes for 2,826 yards, 15 touchdowns and 8 interceptions. Dominique Rhymes and Jalen Philpot have combined for 1,130 receiving yards and 5 touchdowns, while Erik Brooks has 35 receptions.

The Calgary Stampeders ground game is averaging 115.5 yards per contest, and Dedrick Mills leads the way with 882 yards and 8 touchdowns. Defensively, Calgary is allowing 20.4 points and 372 yards per game. Jacob Roberts leads the Calgary Stampeders with 74 tackles, Jaylon Hutchings has 7 sacks and Adrian Greene has 4 interceptions.

Stampeders vs Lions Prediction

Right when it looked like the Stampeders were finding their groove, they suffer a bad loss to the Elks. The Lions enter this game in slightly better form overall, and they’ve won 7 of the last 10 games against the Stampeders. The Lions are the better offensive side, and they can run the ball, which makes them a threat on the road. The Stampeders are 1-4 ATS in their last 5 games when a favorite of 3 or more points, and 3 of those failed covers were outright losses. Give me the Lions and the points on Friday night.

Randy Chambers's Free Pick: Lions +5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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