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Arkansas vs Missouri Prediction 2/21/26 College Basketball Picks Today

Missouri (18-8) vs. Arkansas (19-7)
February 21, 2026 4:00 pm EDT
The Line: Arkansas -10.5; Over/Under: 160.5
(Get latest betting odds)

The Missouri Tigers and Arkansas Razorbacks meet Saturday in college basketball action at the Bud Walton Arena. Here’s a Arkansas vs Missouri Prediction. This article will include a Arkansas vs Missouri Pick.

Missouri Tigers Betting Preview

The Missouri Tigers lost to Texas, beat Vanderbilt, and they play Tennessee next. Missouri has won 5 of its last 7 games.

The Missouri Tigers are averaging 80.1 points on 49 percent shooting and allowing 74.6 points on 42.1 percent shooting. Mark Mitchell is averaging 16.9 points and 5.5 rebounds, while Jayden Stone is averaging 15.1 points and 2.1 assists. Trent Pierce is the third double-digit scorer, and Jacob Crews is dishing 0.3 assists. The Missouri Tigers are shooting 35.4 percent from beyond the arc and 67.9 percent from the free throw line. The Missouri Tigers are allowing 36.2 percent shooting from deep and are grabbing 33 rebounds per game.

Arkansas Razorbacks Betting Preview

The Arkansas Razorbacks beat Auburn, lost to Alabama, and they play Texas A&M next. Arkansas has won 6 of its last 8 games.

The Arkansas Razorbacks are averaging 89.8 points on 50.4 percent shooting and allowing 78.1 points on 44.1 percent shooting. Darius Acuff Jr. is averaging 22.3 points and 3 rebounds, while Meleek Thomas is averaging 15.3 points and 2.7 assists. Trevon Brazile is the third double-digit scorer and Billy Richmond III is grabbing 3.8 rebounds. The Arkansas Razorbacks are shooting 37.7 percent from beyond the arc and 74.2 percent from the free throw line. The Arkansas Razorbacks are allowing 31.1 percent shooting from deep and are grabbing 32.4 rebounds per game.

Why the Arkansas Razorbacks will win

  • Arkansas has won 38 of its last 40 games as an AP-ranked team against a non-AP-ranked team at Bud Walton Arena.
  • Missouri has lost each of its last six games at Bud Walton Arena following a home win.
  • Arkansas has won the first half in each of its last eight February games as an AP-ranked team.

Why the Missouri Tigers will win

  • Arkansas has lost each of its last four day games after coming off overtime.
  • Missouri has won four of its last five games.
  • The road team has won the first half in four of Arkansas’ last five games.

Total Points Facts

  • Each of Arkansas’ last 11 games at Bud Walton Arena have produced a total of 161+ points.
  • Eleven of Missouri’s last 12 day games against AP-ranked opponents have produced a total of 158 or fewer points.

Arkansas vs Missouri Prediction

Arkansas is obviously the more talented team and has been a buzz saw at home. However, Arkansas is also fresh off a heartbreaking loss to Alabama in overtime, and there could be some hangover here. Missouri is also enjoying a nice stretch of ball, just upsetting Vanderbilt while snagging road wins over South Carolina and Texas A&M. Missouri isn’t a bad team, but this line suggests it can’t hang with the big boys. We saw Missouri go into Kentucky last month and win outright as double-digit underdogs. Missouri shoots the ball well enough to put up a fight. Give me the points.

Randy Chambers's Free Pick: Missouri +10.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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