Cincinnati vs Clemson Prediction 12/21/25 College Basketball Picks Today

In this article, we will formulate a Cincinnati vs Clemson Prediction for this College Basketball game on Sunday, December 21^st. Let’s take a look at the prediction for this College Basketball matchup.

Clemson Tigers Preview

Clemson Tigers have a 9-3 record this season and are sitting in 10th place of the ACC. They have a 0-2 road record and are coming off a 68-61 home win against South Carolina. Their previous three games were a 70-63 home win against Mercer, a 67-64 neutral-site loss against BYU, and a 90-84 away loss against Alabama.

Offensively, Clemson averages 80.7 points per game, while allowing 65.9 points per game defensively. The Tigers shoot with 46% from the field and grab 40.3 rebounds per game, while dishing out 14.8 assists per game. They average 2.8 blocks per game and 6.1 steals per game defensively.

RJ Godfrey leads Clemson in scoring, with an average of 11.4 points per game, while shooting with 65% from the field and 76.7% from the free throw line. RJ Godfrey also leads the team in rebounds with 6.2 per game, while Dillon Hunter adds a team-high 2.7 assists per game.

Cincinnati Bearcats Preview

Cincinnati Bearcats have a 7-4 record this season and are sitting in 14th place of the Big 12. They have a 0-1 road record and are coming off an 88-51 home win against Alabama State. Their previous three games were an 84-65 home loss against Georgia, a 79-74 away loss against Xavier, and a 76-58 home win against Tarleton State.

Offensively, Cincinnati averages 75.5 points per game, while allowing 65.5 points per game defensively. The Bearcats shoot with 42% from the field and grab 40.1 rebounds per game, while dishing out 18.0 assists per game. They average 5.5 blocks per game and 7.4 steals per game defensively.

Baba Miller leads Cincinnati in scoring, with an average of 14.7 points per game, while shooting with 63.3% from the field and 58.8% from the free throw line. Baba Miller also leads the team in rebounds with 11.0 per game, while Kerr Kriisa adds a team-high 4.6 assists per game.

Cincinnati Bearcats @ Clemson Tigers Betting Trends: December 21, 2025

Why the Clemson Tigers will win

• Clemson has won each of its last six games against non-AP-ranked opponents.
• Cincinnati has lost four of its last five games played at neutral venues.
• Clemson has won the first half in each of its last five games against non-Conference opponents at Bon Secours Wellness Arena.

Why the Cincinnati Bearcats will win

• Cincinnati has won each of its last nine Sunday games against non-Conference opponents.
• Cincinnati has won the first half in each of its last seven Sunday day games against non-Conference opponents.

Total Points Facts

• Each of Clemson’s last nine games at Bon Secours Wellness Arena have produced a total of 138+ points.
• Each of Cincinnati’s last eight games against non-AP-ranked opponents at a neutral venue have produced a total of 138+ points.

Cincinnati vs Clemson Prediction

In this Cincinnati vs Clemson Prediction, Clemson is coming as -6.5 favorites. Clemson has been the better team this season, as they have a better overall record but both teams have been winless on the road and this game takes place in a neutral site. Cincinnati is 2-3 in its last 5 games and 1-7 against the spread in its last 8, while on the other hand, Clemson is coming off back-to-back wins and are 4-2 against the spread in their last 6. The value here lies in the total, as both teams have been elite defensively, allowing just 131.4 points per game combined and as a result, they are 7-1 to the under in their last 8 games combined. Take the under 137.5 points in this one.