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Cincinnati vs DePaul Prediction 4/1/25 College Basketball Picks Today

DePaul (14-19) vs. Cincinnati (18-15)
April 1, 2025 3:00 pm EDT
The Line: Cincinnati -9.5; Over/Under: 143.5
(Get latest betting odds)

In this article, we will formulate a Cincinnati vs DePaul Prediction for this college basketball game on Tuesday, April 1st, at MGM Arena. Let’s take a look at a Cincinnati Bearcats vs DePaul Blue Demons pick. 

DePaul Made it to a Tournament!

Heading into the season, there was not many expectations about this team, and they still finished with a losing record, but they have to take it as a win that they were even invited to this. DePaul headed into the Big East Tournament as a 10 seed, and in the last game, they were knocked off by Creighton. They were able to force double overtime, but they just ran out of gas late. Layden Blocker was the top player putting up 25 points, five rebounds, and two assists. Three different players put up at least 10 points. 

DePaul has a 14-19 overall record, averaging 72.8 points per game. The defense has been the biggest issue, and they are giving up 74.8 points per game. CJ Gunn has been the top player, averaging 12.8 points while shooting 42.9 percent from the field. 

Why DePaul Will Beat Cincinnati 

  • DePaul has won five of its last six day games against non-Conference opponents.
  • Cincinnati has lost four of its last five games.

A Down Year for Cincinnati

It’s all about perspective, and from Cincinnati’s standpoint, it has been a disappointing year, even though they sit with an 18-15 record. Cincinnati’s last game was against the Iowa State Cyconles, and it was an ugly one. The offense only managed 56 points, while the defense gave up 76 points, and that led to the defeat. At halftime, they were down by nine points, and in the second half, it didn’t get any easier. Guard Jizzle James was the top player putting up 17 points, three rebounds, and two assists. 

Cincinnati is averaging 70.5 points on the season while its defense is giving up 65.7 points per game. They leaned on the defense, which is 26th in the league. James has been the top player overall, averaging 12.8 points while shooting over 40 percent from the field. 

Total Points Facts

  • Each of DePaul’s last five day games against non-Conference opponents have produced a total of 148+ points.
  • Each of Cincinnati’s last five games against the Big East Conference at neutral venues have produced a total of 139 or fewer points.

Why Cincinnati Will Beat DePaul

  • Cincinnati has won 12 of its last 13 day games against non-Conference opponents.
  • DePaul has lost each of its last four games against non-Conference opponents at neutral venues.
  • DePaul has lost the first half in five of its last six games against non-Conference opponents at neutral venues.

Cincinnati vs DePaul Prediction

It might not be a popular play, but I believe DePaul is going to keep this game close. DePaul really looked like they were about to knock off a very good Creighton team in the last game, and I expect their defense is going to be strong again. Cincinnati is averaging 70.5 points per game, and their offense just isn’t going to be good enough here. Will the favorites win? Probably, but this is just way too many points. DePaul’s defense will keep them in it until the last couple of possessions.

Shane Mickle's Free Pick: DePaul +9.5

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Shane Mickle

Sports is about all Shane knows in this life! He has a passion for sports and writing, which makes working for Sportschatplace a perfect job for him! If you find him cheering for a team it's usually a Minnesota team, or the Kansas Jayhawks!

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