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Clemson vs Syracuse Prediction 12/31/25 College Basketball Picks Today

Clemson (10-3) vs. Syracuse (9-4)
December 31, 2025 2:00 pm EDT
The Line: Syracuse +2.5; Over/Under: 141.5
(Get latest betting odds)

In this article, we will formulate a Clemson vs Syracuse Prediction for this College Basketball game on Wednesday, December 31st. Let’s take a look at the prediction for this College Basketball matchup.

Syracuse Orange Preview

Syracuse Orange have a 9-4 record this season and are sitting in the 14th place of the ACC. They have a 8-1 home record and are coming off a 77-48 home win against Stonehill. Their previous three games were a 91-83 home win against New Mexico State, a 76-62 home win against Mercer, and a 70-69 home loss against Hofstra.

Offensively, Syracuse averages 74.6 points per game, while allowing 64.8 points per game defensively. The Orange shoot with 47% from the field and grab 36.5 rebounds per game, while dishing out 13.0 assists per game. They average 7.2 blocks per game and 7.0 steals per game defensively.

J.J. Starling leads Syracuse in scoring, with an average of 11.3 points per game, while shooting with 44.1% from the field and 44.8% from the free throw line. William Kyle III leads the team in rebounds with 8.3 per game, while Naithan George adds a team-high 4.9 assists per game.

Clemson Tigers Preview

Clemson Tigers have a 10-3 record this season and are sitting in the 10th place of the ACC. They have a 0-2 away record and are coming off a 68-65 home win against Cincinnati. Their previous three games were a 68-61 home win against South Carolina, a 70-63 home win against Mercer, and a 67-64 neutral-site loss against BYU.

Offensively, Clemson averages 79.7 points per game, while allowing 65.8 points per game defensively. The Tigers shoot with 46% from the field and grab 39.3 rebounds per game, while dishing out 14.8 assists per game. They average 2.6 blocks per game and 6.1 steals per game defensively.

RJ Godfrey leads Clemson in scoring, with an average of 11.3 points per game, while shooting with 63.3% from the field and 75.0% from the free throw line. RJ Godfrey also leads the team in rebounds with 5.8 per game, while Dillon Hunter adds a team-high 2.8 assists per game.

Clemson Tigers @ Syracuse Orange Betting Trends: December 31, 2025

 

Why the Syracuse Orange will win

  • Syracuse has won 10 of its last 11 home games.
  • Clemson has lost four of its last five games at JMA Wireless Dome.
  • Syracuse has won the first half in each of its last 11 home games.

Why the Clemson Tigers will win

  • Clemson has won each of its last 11 day games against Conference opponents.
  • Syracuse has lost four of its last five day games.
  • Clemson has won the first half in 10 of its last 11 day games against Conference opponents.

Total Points Facts

  • Each of Syracuse’s last six day games against Conference opponents have produced a total of 146+ points.
  • Each of Clemson’s last four games have produced a total of 133 or fewer points.

Clemson vs Syracuse Prediction

In this Clemson vs Syracuse Prediction, Clemson is coming as -1.5 road favorites. Both teams have almost identical records this season but Syracuse has been almost perfect at home, while Clemson has lost both of its road games this season. Both teams have been in excellent form lately, as they are 5-1 and 7-2 in their last six and nine games respectively, so I see no value on either side. Both have been playing excellent defense this season, allowing just 130.6 points per game combined and as a result, they are a perfect 5-0 to the under in their last 5 games combined. Take the under 141.5 points in this one.

Nikos Lagouretos's Free Pick: Under 141.5

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