Depaul vs. Xavier Pick – Basketball Predictions & Odds 1/18/23

Depaul vs. Xavier Pick – Basketball Predictions & Odds 1/18/23 player photo
Credit: USA Today Sports

The Xavier Musketeers and the Depaul Blue Demons meet in college basketball action from the Wintrust Arena on Wednesday night. Let’s dive into the odds, injuries, matchup history and make a prediction for this game.


The Xavier Musketeers are listed as 9-point road favorites coming into this game with an attached ML price of -360. The over/under for this game is set at 156.5 points.


Xavier’s injury report is completely clean while Depaul has listed Caleb Murphy as out with a wrist injury until what appears to be late January at the earliest for a return.

Matchup history

These two teams have traded wins back and forth in each of the last four meetings, with Depaul squeezing out a 69-65 win back on February 5th, 2022.


Xavier is 5-0 ATS in their last 5 games overall and 5-1 ATS in their last 6 road games while the over is 22-7-2 in their last 31 games following an ATS win. Depaul is 5-1 ATS in their last 6 home games and 4-1-1 ATS in their last 6 games overall while the over is 7-2-1 in their last 10 games following a loss.


I’m sticking with Xavier here as I just don’t trust Depaul in a spot like this. Sure, a home underdog is tempting and Depaul can score, but the defense against the better team really slips more often than not for the Blue Demons, and Depaul’s gotten their teeth kicked in by less than what they’re up against here. Blink, and Xavier can hang bunches of points on your in no time and I think Depaul finds that out first hand here. Give me Xavier in a double-digit win.

Chris Ruffolo's Free Pick:Xavier -9