College Basketball Picks

Duke vs Louisville Pick – Basketball Predictions & Odds 2/20/23

Louisville Cardinals (4-23) vs. Duke Blue Devils (19-8)
February 20, 2023 7:00 pm EDT
The Line: Duke Blue Devils -18.5 / Louisville Cardinals +18.5; Over/Under: +137.5
(Get latest betting odds)

The Louisville Cardinals and the Duke Blue Devils meet in college basketball action from the Cameron Indoor Stadium on Monday night. Let’s dive into the odds, injuries, matchup history and make a prediction for this game.


Duke comes into this game listed as an 18.5-point home favorite with the total for this game set at 137.5 points.


For Louisville, Emmanuel Okorafor is listed as questionable for this game with an ankle injury while Duke comes into this game with a clean injury report.

Matchup History

Duke’s 74-65 win back on January 29th, 2022 made it back-to-back wins for the Blue Devils in this head-to-head matchup.


Louisville is 5-1 ATS in their last 6 games overall and 6-13-2 ATS in their last 21 road games while the over is 5-0-1 in their last 6 road games against a team with a winning home record. Duke is 3-10 ATS in their last 13 games overall and 1-4 ATS in their last 5 home games while the under is 5-1-1 in their last 7 games overall.


I’m going to take a shot on Louisville here. Duke’s a solid team and Cameron Indoor’s a tough place to go on the road and compete let alone try to win if you’re a Louisville team that’s been beat up left and right this season. However, Louisville’s been competitive lately and while this is a talented Duke team, it’s still a Duke team that lacks a killer instinct and hasn’t necessarily blown teams out lately. It wouldn’t shock anyone if Louisville got dismantled here, but I’m not trying to lay this many points with this Duke team. I’ll take Louisville and the points.

Chris Ruffolo's Free Pick: Louisville +18.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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