College Basketball Picks

Duke vs Virginia Prediction 2/28/26 College Basketball Picks Today

Virginia (25-3) vs. Duke (26-2)
February 28, 2026 12:00 pm EDT
The Line: Duke -10.5; Over/Under: 139.5
(Get latest betting odds)

The Virginia Cavaliers and Duke Blue Devils meet Saturday in college basketball action at the Cameron Indoor Stadium. Here’s a Duke vs. Virginia prediction. This article will include a Duke vs. Virginia pick.

Virginia Cavaliers Betting Preview

The Virginia Cavaliers beat Miami and NC State, and they play Wake Forest next. Virginia has won 9 straight games.

The Virginia Cavaliers are averaging 82.3 points on 46.8 percent shooting and allowing 67.8 points on 39.3 percent shooting. Thijs De Ridder is averaging 16 points and 6.3 rebounds, while Malik Thomas is averaging 12.3 points and 1.7 assists. Sam Lewis is the third double-digit scorer and Chance Mallory is grabbing 4 rebounds. The Virginia Cavaliers are shooting 36.3 percent from beyond the arc and 71.1 percent from the free throw line. The Virginia Cavaliers are allowing 30 percent shooting from deep and are grabbing 37.6 rebounds per game.

Duke Blue Devils Betting Preview

The Duke Blue Devils beat Michigan and Notre Dame, and they play NC State next. Duke has won 10 of its last 11 games.

The Duke Blue Devils are averaging 83.1 points on 49.8 percent shooting and allowing 62.9 points on 39.2 percent shooting. Cameron Boozer is averaging 22.7 points and 10.1 rebounds, while Isaiah Evans is averaging 14.5 points and 3 rebounds. Patrick Ngongba II is the third double-digit scorer and Caleb Foster is grabbing 3.6 rebounds. The Duke Blue Devils are shooting 34.9 percent from beyond the arc and 72.5 percent from the free throw line. The Duke Blue Devils are allowing 30.6 percent shooting from deep and are grabbing 37.2 rebounds per game.

Why the Duke Blue Devils will win

  • Duke has won each of its last 30 games at Cameron Indoor Stadium.
  • Virginia has lost 10 of its last 11 games against AP-ranked opponents.
  • Duke has won the first half in each of its last 22 February games as a top-10 AP-ranked team.

Why the Virginia Cavaliers will win

  • Virginia has won each of its last nine games.
  • Duke has lost each of its last three games as a top-3 AP-ranked team against a top-15 AP-ranked team at Cameron Indoor Stadium.
  • Virginia has won the first half in seven of its last eight day games as a top-15 AP-ranked team against a top-15 AP-ranked team.

Total Points: Facts

  • Nine of Duke’s last 10 day games against conference opponents at Cameron Indoor Stadium have produced a total of 143+ points.
  • Four of Virginia’s last five games against Top 5 AP-ranked opponents have produced a total of 142+ points.

Duke vs Virginia Prediction

Duke is going to be favored at home because it’s Duke but this line is absolutely insane. Virginia remains elite defensively but also has more offensive spark than past Virginia teams. Virginia is 8-1 SU on the road. Virginia is a tough-minded, well-balanced team that can beat anybody in the country any given night. This line feels inflated and disrespectful toward a good Virginian side. I’ll gladly grab the points.

Randy Chambers's Free Pick: Virginia +10.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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