Iowa State vs Ole Miss Prediction 3/23/25 College Basketball Picks Today

The Iowa State Cyclones and the Ole Miss Rebels meet Saturday in college basketball action from the Fiserv Forum. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Iowa State vs Ole Miss Prediction.

Iowa State Recap

The Iowa State Cyclones booked their spot in the Second Round of the NCAA Tournament after ending up with an 82-55 win over Lipscomb in the opening round in their last game.

Cyclones Looking To Make Back-To-Back Sweet 16 Appearances

Curtis Jones leads the Cyclones in scoring with 17.1 PPG along with 4.3 RPG and 2.3 APG. Keshon Gilbert has 13.4 PPG with 3.5 RPG and a team-high 4.1 APG to lead the Cyclones in assists, but is expected to be out for the rest of the year with an injury. Milan Momcilovic has 11.4 PPG with 3.2 RPG while Joshua Jefferson has 13 PPG with a team-high 7.4 RPG to lead Iowa State on the glass up to this point in the year. Tamin Lipsey has 10.8 PPG with 3.2 APG and 2.1 SPG to cap off the scoring in double figures for Iowa State so far this season. Dishon Jackson has 8.6 PPG with 5.1 RPG as well on the year. As a team, Iowa State is averaging 80.4 PPG on 48% shooting from the field, 35.8% from three and 75.7% from the foul line this season.

Why the Iowa State Cyclones will win

• Iowa State has won each of its last seven games against non-Conference opponents.
• Ole Miss has lost 24 of its last 27 games against AP-ranked opponents.

Ole Miss Recap

The Ole Miss Rebels come into the Round of 32 after picking up a win over North Carolina by a final score of 71-64 in their opening NCAA Tournament matchup.

Rebels Looking For Second All-Time Sweet 16 Appearance, First Since 2001

Sean Pedulla leads the Rebels in scoring, assists and steals with 15 PPG along with 3.6 RPG and 3.6 APG and 1.8 SPG while Jaylen Murray has 10.5 PPG with 3.5 APG. Matthew Murrell has 10.5 PPG and Dre Davis has 10.5 PPG with 4.8 RPG. Jaemyn Brakefield has 10.9 PPG with 4.3 RPG. Malik Dia has 10.5 PPG with a team-high 5.7 RPG to lead the Rebels on the glass and to cap off the group of double-digit scorers for Ole Miss so far this season. As a team, Ole Miss is averaging 77.2 PPG on 44.2% shooting from the field, 34.1% from three and 73.8% from the foul line this season.

Why the Ole Miss Rebels will win

• Ole Miss has won each of its last 15 night games against non-Conference opponents.
• Iowa State has lost each of its last three games against the Southeastern Conference.

Total Points Facts

• Fifteen of Iowa State’s last 16 night games at a neutral venue have produced a total of 142 or fewer points.
• Seven of Ole Miss’ last eight games against AP-ranked opponents have produced a total of 152+ points.

Iowa State vs Ole Miss Prediction

I’m on Iowa State in this game. I just think the Cyclones are the better team by a fair margin, and Ole Miss was really lucky to escape from UNC in that first round matchup. Had UNC not dug themselves into a big hole early, we could be talking about a completely different second round matchup. The Cyclones may be banged up without Keshon Gilbert, but the Cyclones showed there’s more to this team than one body, and I think that the Cyclones get the win and cover here. Give me Iowa State.