Louisville vs Creighton Prediction 3/20/25 College Basketball Picks Today
Creighton (24-10) vs. Louisville (27-7)
March 20, 2025 12:15 pm EDT
The Line: Louisville -2.5; Over/Under: 145.5
(Get latest betting odds)
The Creighton Bluejays and Louisville Cardinals meet Thursday in the college basketball First Round at the Rupp Arena. Here’s a Louisville vs Creighton Prediction. This article will include a Louisville vs Creighton Pick.
Creighton Bluejays Betting Preview
The Creighton Bluejays recently played Butler, DePaul, UCONN, and St. John’s. Creighton has lost back-to-back games twice since November 30.
The Creighton Bluejays are averaging 75.4 points on 47.7 percent shooting and allowing 69 points on 40.7 percent shooting. Ryan Kalkbrenner is averaging 19.4 points and 8.8 rebounds, while Steven Ashworth is averaging 16.3 points and 4.1 rebounds. Pop Isaacs is the third double-digit scorer and Jamiya Neal is grabbing 6.1 rebounds. The Creighton Bluejays are shooting 34.4 percent from beyond the arc and 74.1 percent from the free throw line. The Creighton Bluejays are allowing 31.9 percent shooting from deep and are grabbing 34.9 rebounds per game.
Louisville Cardinals Betting Preview
The Louisville Cardinals recently played Cal, Stanford, Clemson, and Duke. Louisville hasn’t lost back-to-back games since December 3-8.
The Louisville Cardinals are averaging 79.3 points on 45.6 percent shooting and allowing 68.5 points on 42.4 percent shooting. Terrence Edwards Jr. is averaging 16.6 points and 4.1 rebounds, while Chucky Hepburn is averaging 16.2 points and 3.5 rebounds. Reyne Smith is the third double-digit scorer and J’Vonne Hadley is grabbing 7.3 rebounds. The Louisville Cardinals are shooting 33.3 percent from beyond the arc and 74.9 percent from the free throw line. The Louisville Cardinals are allowing 33.3 percent shooting from deep and are grabbing 35.1 rebounds per game.
Why the Louisville Cardinals will win
- Louisville has won each of its last 10 games against non-AP-ranked opponents.
- Creighton has lost each of its last four games against Top 10 AP-ranked opponents.
- Louisville has won the first half in 22 of its last 23 games.
Why the Creighton Bluejays will win
- Louisville has lost each of its last six games at Rupp Arena at Central Bank Center.
- Creighton has won each of its last four games against the Atlantic Coast Conference.
- Creighton has won the first half in each of its last seven NCAA Tournament games.
Total Points Facts
- Thirteen of Louisville’s last 14 day games against the Big East Conference have produced a total of 143 or fewer points.
- Seven of Creighton’s last eight games against Top 10 AP-ranked opponents have produced a total of 148+ points.
Matchup/League Facts
- Louisville ranks 17th among Division 1 teams for three-point field goal attempts per game this season (29.0).
- Louisville ranks 25th among Division 1 teams for net rating this season (+15.7).
- Creighton ranks 2nd among Division 1 teams for opponent free throws made per game this season (8.2).
- Creighton ranks 2nd among Division 1 teams for opponent free throw attempts per game this season (11.4).
Louisville vs Creighton Injury Report
Louisville doesn’t have a player listed on its injury report. Creighton will be without Pop Isaacs and Larry Johnson, while Fedor Zugic is questionable with an ankle injury.
Louisville vs Creighton Prediction
Louisville is a tough-minded team that gets physical with its opponent and probably should be favored with this game being in Lexington. It’s pretty much a home game for Louisville. With that said, the value is with Creighton and the points, as the Bluejays can score the basketball with the best of them and have an above-average defense that’s top-40 in defensive field goal percentage.
Creighton is far from a pushover and if it can control the pace early and hit some shots, this is a game it could win outright. I’ll grab the bucket with Creighton in the first game of the first round.
