Memphis vs Louisville Prediction 12/13/25 College Basketball Picks Today

In this article, we will formulate a Memphis vs Louisville Prediction for this College Basketball game on Saturday, December 13^th. Let’s take a look at the prediction for this College Basketball matchup.

Louisville Cardinals Preview

Louisville Cardinals have an 8-1 record this season and are sitting on the 5th place of the Atlantic Coast. They have a 6-0 home record and are coming off a 87-78 home win against Indiana. Their previous three games were a loss against Arkansas by 89-80, a win against NJIT by 104-47 and a win against Eastern Michigan by 87-46.

Offensively, Louisville average 93.8 points per game, while allowing 67.6 points per game defensively. The Cardinals shoot with 47% from the field and grab 43.6 rebounds per game, while dishing out 19.2 assists per game. They average 3.9 blocks per game and 8.6 steals per game defensively. Ryan Conwell leads Louisville in scoring, with an average of 19.7 points per game, while shooting with 42.9% from the field and 85.5% from the free throw line.

Memphis Tigers Preview

Memphis Tigers have a 4-4 record this season and are sitting on the 9th place of the American. They have a 0-1 away record and are coming off a 78-71 home win against Baylor. Their previous three games were a win against New Orleans by 86-70, a win against Southern Illinois by 74-58 and a loss against Wake Forest by 69-68.

Offensively, Memphis average 76 points per game, while allowing 74.1 points per game defensively. The Tigers shoot with 43% from the field and grab 37.5 rebounds per game, while dishing out 14.8 assists per game. They average 4.3 blocks per game and 8.3 steals per game defensively. Doug McDaniel leads Memphis in scoring, with an average of 13.9 points per game, while shooting with 38% from the field and 88.9% from the free throw line.

Memphis Tigers @ Louisville Cardinals Betting Trends: December 13, 2025

Why the Louisville Cardinals will win

• Louisville has won each of its last 19 games at KFC Yum! Center against non-AP-ranked opponents.
• Louisville has won the first half in each of its last 16 games at KFC Yum! Center.

Why the Memphis Tigers will win

• Memphis has won six of its last seven games against the Atlantic Coast Conference.
• Memphis has won the first half in each of its last four games.

Total Points Facts

• Twenty of Louisville’s last 21 games against the American Conference Conference have produced a total of 157 or fewer points.
• Seventeen of Memphis’ last 18 Saturday day games against non-Conference opponents have produced a total of 157 or fewer points.

Memphis vs Louisville Prediction

In this Memphis vs Louisville Prediction, Louisville is coming as -14.5 home favorites. Louisville has been the far better team this season as they have lost only once in their nine games played and have been undefeated at home. They will be playing their seventh game at home out of their ten played this season and are 4-1 against the spread in their last 5 games. Louisville is better both offensively and defensively than Memphis, scoring 17.8 points per game more while allowing 6.5 points per game less and have a +26.2 point differential this season. The value here lies with the home team, so take Louisville and lay the points.