Memphis vs Vanderbilt Prediction 12/17/25 College Basketball Picks Today
Vanderbilt (10-0) vs. Memphis (4-5)
December 17, 2025 7:00 pm EDT
The Line: Memphis +7.5; Over/Under: 159.5
(Get latest betting odds)
The Vanderbilt Commodores and Memphis Tigers meet Wednesday in the college basketball action at the FedExForum. Here’s a Memphis vs Vanderbilt Prediction. This article will include a Memphis vs Vanderbilt Pick.
Vanderbilt Commodores Betting Preview
The Vanderbilt Commodores beat SMU and Central Arkansas, and they play Wake Forest next. Vanderbilt has won 10 straight games.
The Vanderbilt Commodores are averaging 95.4 points on 51.6 percent shooting and allowing 72.9 points on 39.7 percent shooting. Duke Miles is averaging 16.6 points and 4.2 assists, while Tyler Tanner is averaging 15.8 points and 3.2 rebounds. Tyler Nickel is the third double-digit scorer and Devin McGlockton is grabbing 7 rebounds. The Vanderbilt Commodores are shooting 37.5 percent from beyond the arc and 75.8 percent from the free throw line. The Vanderbilt Commodores are allowing 30.7 percent shooting from deep and are grabbing 35.8 rebounds per game.
Memphis Tigers Betting Preview
The Memphis Tigers beat Baylor, lost to Louisville, and they play Mississippi State next. Memphis has split its last 6 games.
The Memphis Tigers are averaging 75.8 points on 43 percent shooting and allowing 77 points on 42.7 percent shooting. Dug McDaniel is averaging 14.1 points and 3 rebounds, while Sincere Parker is averaging 9.3 points and 2.9 rebounds. Zach Davis is dishing 1.6 assists and Julius Thedford is grabbing 5.1 rebounds. The Memphis Tigers are shooting 32.1 percent from beyond the arc and 70.2 percent from the free throw line. The Memphis Tigers are allowing 34.7 percent shooting from deep and are grabbing 32.3 rebounds per game.
Why the Memphis Tigers will win
- Memphis has won each of its last 15 night games against non-Conference opponents at FedExForum.
- Vanderbilt has lost four of its last five games against the American Conference.
- Memphis has won the first half in 28 of its last 32 night games against non-Conference opponents at FedExForum.
Why the Vanderbilt Commodores will win
- Vanderbilt has won each of its last 10 games.
- Memphis has lost 20 of its last 24 night games against AP-ranked opponents.
- Vanderbilt has won the first half in each of its last 17 games against non-Conference opponents.
Total Points Facts
- Each of Vanderbilt’s last 14 Wednesday night games against non-Conference opponents have produced a total of 158 or fewer points.
- Each of Memphis’ last seven night games at FedExForum have produced a total of 156 or fewer points.
Matchup/League Facts
- Vanderbilt ranks 1st among Division 1 teams for opponent steals per game this season (4.2).
- Vanderbilt ranks 1st among Division 1 teams for opponent blocks per game this season (1.3).
Memphis vs Vanderbilt Prediction
This is the best Vanderbilt team we’ve seen in recent memory and deserves to be a big favorite. Memphis has also had issues finishing games. So, you can understand why the line is what it is. However, Memphis has competed this season, and it’s led to covers in 7 of its last 9 games. Memphis has an upset win over Baylor, and it nearly beat Wake Forest and Ole Miss. despite having just one double-digit scorer, Memphis plays hard and finds ways to hang around. I don’t expect that effort to go away at home with an undefeated team coming to town. Give me the points with Memphis.