Northwestern vs Ohio State Prediction 12/6/25 College Basketball Picks Today
Ohio State (6-1) vs. Northwestern (5-3)
December 6, 2025 2:00 pm EDT
The Line: Northwestern -1.5; Over/Under: 153.5
(Get latest betting odds)
The Ohio State Buckeyes and Northwestern Wildcats meet Saturday in the college basketball action at the Welsh-Ryan Arena. Here’s a Northwestern vs Ohio State Prediction. This article will include a Northwestern vs Ohio State Pick.
Ohio State Buckeyes Betting Preview
The Ohio State Buckeyes beat Mount St. Marys, lost to Pitt, and they play Illinois next. Ohio State has won 6 of its last 7 games.
The Ohio State Buckeyes are averaging 88.7 points on 52.3 percent shooting and allowing 67.4 points on 41 percent shooting. Bruce Thornton is averaging 20.6 points and 5.3 rebounds, while Christoph Tilly is averaging 15.3 points and 5.3 rebounds. John Mobley Jr. is the third double-digit scorer and Devin Royal is grabbing 5.3 rebounds. The Ohio State Buckeyes are shooting 37.5 percent from beyond the arc and 79.8 percent from the free throw line. The Ohio State Buckeyes are allowing 25.7 percent shooting from deep and are grabbing 35.8 rebounds per game.
Northwestern Wildcats Betting Preview
The Northwestern Wildcats lost to Oklahoma State and Wisconsin, and they play Jackson State next. Northwestern has lost 3 of its last 4 games.
The Northwestern Wildcats are averaging 92.6 points on 50.4 percent shooting and allowing 81.7 points on 38.5 percent shooting. Nick Martinelli is averaging 19.8 points and 6.8 rebounds, while Arrinten Page is averaging 15.8 points and 6.9 rebounds. Jayden Reid is the third double-digit scorer and Tre Singleton is grabbing 5.5 rebounds. The Northwestern Wildcats are shooting 35.9 percent from beyond the arc and 72.9 percent from the free throw line. The Northwestern Wildcats are allowing 29.2 percent shooting from deep and are grabbing 34.6 rebounds per game.
Why the Northwestern Wildcats will win
- The home team has won each of Ohio State’s last seven games.
- Ohio State has lost each of its last five day games against Conference opponents.
- Northwestern has won the first half in each of its last eight games at Welsh-Ryan Arena.
Why the Ohio State Buckeyes will win
- Northwestern has lost 10 of its last 11 day games against Conference opponents.
- Ohio State has won five of its last six games when playing with a rest advantage.
- Ohio State has won the first half in five of its last six road games against Conference opponents.
Total Points Facts
- Each of Northwestern’s last 10 games against Conference opponents at Welsh-Ryan Arena have produced a total of 152 or fewer points.
- Each of Ohio State’s last four day games against non-AP-ranked opponents have produced a total of 150 or fewer points.
Northwestern vs Ohio State Prediction
I was high on Ohio State entering the season and said this should be a team that makes the big dance. Ohio State has looked the part, but it also has had a cake schedule up to this point, and just lost to Pitt as a big favorite. Northwestern isn’t sexy and has three losses already, but it’s always a tough team at home and a psychical group nobody wants to play. Northwestern is an annoying group that competes. Northwestern went blow for blow with Virginia, beat South Carolina, battled with Oklahoma State. Ohio State could get frustrated in a game like this. I’ll give the slight edge to Northwestern at home.