South Carolina vs Butler Prediction 11/21/25 College Basketball Picks Today

In this article, we will formulate a South Carolina vs Butler Prediction for this College Basketball game on Friday, November 21^st. Let’s take a look at the prediction for this College Basketball matchup.

Butler Bulldogs Preview

Butler has a 3-1 record this season and are tied for 4th place in the Big East conference. They are 4-0 ATS, 2-2 in Over/Under and have a 3-0 home record and a 0-1 away record. Butler is coming off an 85-87 road loss against Southern Methodist and will face Virginia, Wright State and Eastern Michigan next.

Offensively, Butler averages 95.8 points per game, which ranks 15th in the nation, while defensively, they allow 72.8 points per game (181st). The Bulldogs shoot with 49.0% from the field (83rd), and with 40.2% from beyond the arc (30th). They shoot with 67.2% from the free throw line (275th), and grab 46.3 rebounds per game (12th), while dishing out 21.0 assists per game (11th) and committing 15.3 turnovers per game (321st).

Finley Bizjack leads Butler in scoring, with an average of 15 points and 3 assists. Michael Ajayi follows with 14.8 points and 11 rebounds and 4 assists per game, while Jamie Kaiser adds 11.5 points and 5 rebounds per game.

South Carolina Gamecocks Preview

South Carolina has a 4-0 record this season and are tied for 5th place in the SEC conference. They are 2-2 ATS, 3-1 in Over/Under and have a 4-0 home record and a 0-0 away record. South Carolina is coming off an 87-58 home win against Radford and will face Northwestern, Charleston Southern and Virginia Tech next.

Offensively, South Carolina averages 85.5 points per game, which ranks 100th in the nation, while defensively, they allow 67.5 points per game (88th). The Gamecocks shoot with 46.9% from the field (131st), and with 36% from beyond the arc (108th). They shoot with 77.5% from the free throw line (44th), and grab 39 rebounds per game (261st), while dishing out 19.8 assists per game (26th) and committing 11.5 turnovers per game (122nd).

Meechie Johnson Jr. leads South Carolina in scoring, with an average of 14.5 points and 3 assists. Eli Ellis follows with 13.5 points and 4 assists per game, while Mike Sharavjamts adds 11.5 points and 6 rebounds per game.

South Carolina Gamecocks @ Butler Bulldogs Betting Trends: November 21, 2025

Why the Butler Bulldogs will win

• South Carolina has lost eight of its last nine day games.
• Butler has won each of its last five Friday day games played at neutral venues.
• Butler has won the first half in each of its last four games.

Why the South Carolina Gamecocks will win

• South Carolina has won each of its last 11 games against non-Conference opponents.
• South Carolina has won the first half in each of its last four games.

South Carolina vs Butler Prediction

In this South Carolina vs Butler Prediction, Butler is coming as -2.5 home favorites. Both teams have been excellent this season, as Butler has lost only once in its 4 games played, while South Carolina has been undefeated this season. Both teams have been playing elite defense, scoring 181.3 points per game combined, with Butler being the 15^th-best team in the country offensively and as a result, both teams are a combined 7-1 to the over in their last 8 games. Take the over 154.5 points once again.