USC vs Seton Hall Prediction 11/26/25 College Basketball Picks Today
Seton Hall (6-0) vs. USC (5-0)
November 25, 2025 5:00 pm EDT
The Line: USC -7.5; Over/Under: 146.5
(Get latest betting odds)
The Seton Hall Pirates and the USC Trojans meet Tuesday in college basketball action from the Lahaina Civic Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a USC vs Seton Hall Prediction.
Seton Hall Pirates Recap
The Seton Hall Pirates come into this game looking to add on to their 85-74 win over NC State to sit at 6-0 this season.
Pirates Looking To Stay Unbeaten
Tajuan Simpkins leads the Pirates in scoring with 13.2 PPG along with 4 RPG while AJ Staton-McCray has 10.4 PPG with 3.4 RPG as the only other double-digit scorer for Seton Hall up to this point in the year. Elijah Fisher has 8.8 PPG with 3.4 RPG and Adam Clark has 8.6 PPG with a team-high 4.4 APG to lead Seton Hall in assists. Stephon Payne has 8.4 PPG with 5.8 RPG and Najai Hines has a team-high 6.8 RPG to lead Seton Hall in rebounding so far this season. As a team, Seton Hall is averaging 73 PPG on 41.7% shooting from the field, 33% from three and 75.2% from the foul line this season.
Why the Seton Hall Pirates will win
- Seton Hall has won each of its last six games.
- USC has lost three of its last four games against the Big East Conference.
USC Trojans Recap
The USC Trojans come into this game looking to add on to their 70-67 win over Boise State last time out to sit at 5-0 on the year.
Trojans Win 5 Straight To Start The Year
Rodney Rice leads the Trojans in scoring and assists with 21.8 PPG and 6.8 APG and 4 RPG while Chad Baker-Mazara has 20.2 PPG with a team-high 7 RPG to lead USC in rebounding so far this season. Ezra Ausar has 16.4 PPG with 4.8 RPG and Jacob Cofie has 10 PPG with 6.8 RPG to round out the group of double-digit scorers for USC up to this point in the year. As a team, USC is averaging 94.4 PPG on 47% shooting from the field, 36.8% from three and 70% from the foul line this season.
Why the USC Trojans will win
- USC has won each of its last six day games against non-Conference opponents.
- Seton Hall has lost 11 of its last 12 day games against non-AP-ranked opponents.
Total Points Facts
- Each of Seton Hall’s last 17 games against non-AP-ranked opponents have produced a total of 141 or fewer points.
- Five of USC’s last six games against the Big East Conference have produced a total of 146 or fewer points.
USC vs Seton Hall Prediction
I’m on the Pirates and the points in this game. I just think that Seton Hall has passed my eye test to this point. While I was unsure of how they’d do against NC State, the Pirates put those doubts to rest by dominating a solid Wolfpack team for 40 minutes. USC needed a lot to edge out Boise State and on a quick turnaround, I think Seton Hall is live in this game. Give me the Pirates and the points.