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Vanderbilt vs Nebraska Prediction 3/21/26 College Basketball Picks Today

Vanderbilt (27-8) vs. Nebraska (27-6)
March 21, 2026 8:45 pm EDT
The Line: Nebraska +2.5; Over/Under: 147.5
(Get latest betting odds)

In this article, we will formulate a Vanderbilt vs Nebraska Prediction for this NCAA Tournament 2nd Round matchup on Saturday, March 21st. Let’s take a look at the prediction for this college basketball matchup.

Nebraska Cornhuskers Preview

The Nebraska Cornhuskers have a 27-6 overall record and a 15-5 record in the Big Ten. They are coming off a 76-47 win against Troy and their previous three games were a 74-58 loss against Purdue, an 84-75 win against Iowa and a 72-52 road loss against UCLA.

Offensively, Nebraska averages 77.2 points per game, while allowing 65.6 points per game defensively. The Cornhuskers shoot with 46% from the field and grab 35 rebounds per game, while dishing out 18 assists per game. They average 2.5 blocks per game and 7.3 steals per game defensively.

Pryce Sandfort leads Nebraska in scoring, with an average of 18 points per game, while shooting with 47.3% from the field and 85.7% from the free throw line. Rienk Mast is the team’s leading rebounder with 5.8 per game. Sam Hoiberg leads the team in assists with 4.3 per game.

Vanderbilt Commodores Preview

The Vanderbilt Commodores have a 27-8 overall record and an 11-7 record in the SEC. They are coming off a 78-68 win against McNeese and their previous three games were an 86-75 loss against Arkansas, a 91-74 win against Florida and a 75-68 win against Tennessee.

Offensively, Vanderbilt averages 86.1 points per game, while allowing 75 points per game defensively. The Commodores shoot with 48% from the field and grab 35.4 rebounds per game, while dishing out 16.3 assists per game. They average 4.5 blocks per game and 8 steals per game defensively.

Tyler Tanner leads Vanderbilt in scoring, with an average of 19.3 points per game, while shooting with 48.8% from the field and 86.1% from the free throw line, adding a team-high 5.1 assists. Devin McGlockton is the team’s leading rebounder with 6.7 per game.

Vanderbilt Commodores @ Nebraska Cornhuskers Betting Trends: March 21, 2026

 

Why the Nebraska Cornhuskers will win

  • Nebraska has won each of its last 23 games against non-Conference opponents.
  • Vanderbilt has lost 11 of its last 13 night games against AP-ranked opponents.
  • Nebraska has won the first half in four of its last five games against non-Conference opponents.

Why the Vanderbilt Commodores will win

  • Vanderbilt has won each of its last 14 games against non-Conference opponents.
  • Nebraska has lost each of its last four games against AP-ranked opponents.
  • Vanderbilt has won the first half in each of its last 21 games against non-Conference opponents.

Total Points Facts

  • Each of Vanderbilt’s last nine night games against non-Conference opponents have produced a total of 147+ points.
  • Eight of Nebraska’s last nine night games at a neutral venue have produced a total of 150+ points.

Matchup/League Facts

  • Nebraska ranks 5th among Division 1 teams for opponent free throw attempts per game this season (14.5).
  • Nebraska ranks 6th among Division 1 teams for assist to turnover ratio this season (1.85).
  • Vanderbilt ranks 13th among Division 1 teams for points per game this season (86.9).
  • Vanderbilt ranks 14th among Division 1 teams for free throw percentage this season (78.3%).

Vanderbilt vs Nebraska Prediction

In this Vanderbilt vs Nebraska Prediction, Vanderbilt is coming as -2.5 favorites. Nebraska destroyed Troy in the first round by 29 points, while Vandy is just 4-6 against the spread in its last 10 games. Nebraska is 5-5 ATS in its last 10 and have a superior defense, but I don’t trust them as such small dogs. I prefer the under in this game, as both teams went under in their first-round matchups and are 6-2 to the under in their last 8 games combined. Go under the 147.5 points.

Nikos Lagouretos's Free Pick: Under 147.5

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