Virginia Tech vs Louisville Prediction 2/25/25 College Basketball Picks Today

The Louisville Cardinals and the Virginia Tech Hokies meet Tuesday in college basketball action from Cassell Coliseum. Here’s a Virginia Tech vs Louisville prediction. We will look at this from a betting perspective and determine the best Virginia Tech vs Louisville pick.

Louisville Cardinals Betting Preview

Louisville really only has one bad stretch of games this year; otherwise, it’s been a very nice run in the record column. The Cardinals only lost one of their first six games (versus Tennessee on November 9), then hit a 1-4 run with a lone win over UTEP amid losses to Oklahoma, Ole Miss, Duke, and Kentucky. After a winning streak over Florida State, Eastern Kentucky, North Carolina, Virginia, Clemson, Pitt, Syracuse, Virginia, SMU, and Wake Forest, the Cardinals took another loss to Georgia Tech. The next four games were all wins over Boston College, Miami, NC State, and Notre Dame, giving the Cardinals a 20-6 overall run through 26 games.

In their Saturday matchup with Florida State, the Cardinals jumped out to a 45-31 halftime lead. Louisville posted a 50-44 deficit the rest of the way but still powered out the win 89-81 in the end. Chucky Hepburn led the team with 29 points, five steals, three rebounds, and two assists. J’Vonne Hadley doubled up on 18 points with 11 rebounds, one assist, one steal, and one block in 38 minutes of work. Terrence Edwards had 16 points with two assists, and Reyne Smith added 11 points with three rebounds and one assist. Tops off the bench was Khani Rooths with six points and four boards in 15 minutes on the floor.

Virginia Tech Hokies Betting Preview

Over on the Virginia Tech side, they’ve had a few brief runs of solid play this year but otherwise, it’s been a struggle. The Hokies went 5-8 in their first 13 games, taking losses to Penn State, Jacksonville, Michigan, South Carolina, Vanderbilt, Pitt, Saint Joseph’s, and Duke in that time. A 3-1 run came next with a loss to Stanford amid wins over Miami, Cal, and NC State. Virginia Tech would go just 3-6 over the next nine games with wins over Florida State, Virginia, and Notre Dame among losses to Wake Forest, Georgia Tech, Clemson, SMU, Virginia, and Boston College. That would give the Hokies an 11-15 record through their first 26 outings of the year.

Matched up against Miami over the weekend, Virginia Tech went into the break with a 38-38 tie. The Hokies came back with a 43-30 run the rest of the way and powered out the win at the end 81-68, though. Virginia Tech’s Jaydon Young was the leading team scorer with 27 points, three assists, two steals, and two rebounds in 25 minutes off the bench.

Virginia Tech vs Louisville Prediction

I’ll lean toward Louisville. The Cardinals are coming off a fairly even game versus Florida State. Both teams shot upwards of 50 percent, and Louisville had a modest 31-27 rebounding edge. Even the turnovers were comparable, but Louisville scored 17 points off 14 Seminoles turnovers and Florida State had just seven points off 13 Cardinals miscues. In any case, it was another solid home win that extends Louisville’s streak to five—and they’ve lost just one game since December 14 (Kentucky) in total. Louisville is scoring well also, with 75 or more points in all five of their current victories.

As for Virginia Tech, they didn’t have too many issues with a struggling Miami team over the weekend—even on the road. The Hokies shot a nice 52.5 percent from the field in that one and had just five turnovers, though they did get outfoxed mildly on the boards 31-29. Still, it was a nice total (81) following a miserable 36 points in the road loss to Boston College. That said, Virginia Tech will be in for another tough matchup here, and I don’t quite think they’ll keep pace with Louisville.