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Xavier vs Santa Clara Prediction 11/10/25 College Basketball Picks Today

Santa Clara (2-0) vs. Xavier (2-0)
November 10, 2025 8:30 pm EDT
The Line: Xavier -2.5; Over/Under: 157.5
(Get latest betting odds)

The Santa Clara Broncos and the Xavier Musketeers meet Monday in college basketball action from the Cintas Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Santa Clara Broncos vs. Xavier Musketeers prediction.

Santa Clara Broncos Recap

The Santa Clara Broncos come into this game looking to build on their 2-0 start to the year after a 79-67 win over McNeese last time out. After this game, Santa Clara will head home for a game against Nevada.

Broncos Win Back-To-Back Games To Start Year

Elijah Mahi leads the Broncos in scoring with 16.5 PPG, 3.5 RPG and 2.5 APG while Sash Gavalyugov has 13.5 PPG with 2.5 RPG. Christian Hammond has 12.5 PPG with a team-high 8.5 RPG and 3 APG along with 2.5 SPG and Jake Ensminger has 11.5 PPG with 6 RPG and a team-high 5 APG to lead Santa Clara in the assist department to cap off the group of double-digit scorers for Santa Clara as the Broncos’ leading assist man. Thierry Darlan has 8.5 PPG with 8 RPG and Allen Graves has 6.5 PPG with 8.5 RPG to share the lead for the Broncos on the glass. As a team, Santa Clara is averaging 81 PPG on 43.6% shooting from the field, 56.3% from three and 32.8% from the foul line this season.

Why the Santa Clara Broncos will win

  • Santa Clara has won seven of its last eight games against non-Conference opponents.

Xavier Musketeers Recap

The Xavier Musketeers come into this game looking to build on a 74-69 win over Le Moyne last time out to sit at 2-0 on the year as well. After this game, Xavier will head on the road for a game against the Iowa Hawkeyes.

Musketeers Looking To Defend Home Court

Malik Messina-Moore leads the Musketeers in scoring and assists with 16.5 PPG and 3.5 APG while Tre Carroll has 11 PPG with 4.5 RPG and 2.5 APG and Roddie Anderson III has 11 PPG with 3.5 RPG and 3 APG along with a team-high 2 SPG. Jovan Milicevic has 10 PPG with 3 RPG and All Wright has 10 PPG to cap off the group of double-digit scorers for Xavier so far this season. Filip Borovicanin has a team-high 6.5 RPG as well to lead the Musketeers on the glass. As a team, Xavier is averaging 70 PPG on 38.4% shooting from the field, 39.2% from three and 70.8% from the foul line this season.

Why the Xavier Musketeers will win

  • Xavier has won each of its last 11 games against non-Conference opponents at Cintas Center.

Total Points Facts

  • Each of Xavier’s last 10 games at Cintas Center have produced a total of 154 or fewer points.
  • Five of Santa Clara’s last six games against non-Conference opponents have produced a total of 158+ points.

Santa Clara Broncos vs. Xavier Musketeers Prediction

I’m on the Broncos and the points in this one. I get the case to be made for Xavier at home, but the problem here is that the Musketeers haven’t looked all that impressive against inferior teams through their first two games of the season. Santa Clara gets overlooked time and time again, because they’re in the shadows of Gonzaga and Saint Mary’s in the WCC, but Herb Sendek has a squad here and I think the Broncos at least keep it close. Give me Santa Clara here.


Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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