Arizona State vs TCU Prediction Football Picks Today 9/26/25
TCU Horned Frogs (3-0) vs. Arizona State Sun Devils (3-1)
September 26, 2025 9:00 pm EDT
The Line: Arizona State Sun Devils -3; Over/Under: 54.5
(Get latest betting odds)
Arizona State and TCU meet Friday in Week 5 college football action from the Sun Devil Stadium. Here’s an Arizona State vs TCU prediction. We will look at this from a betting perspective and determine the best Arizona State Sun Devils and TCU Horned Frogs pick.
What a Win for Arizona State
Arizona State had a disappointing loss earlier in the season against Mississippi State, but they sure have to feel good about their last victory. Arizona State scored 14 points in the 4th quarter and that was enough to pick up the 27-24 victory over Baylor. Sam Leavitt completed 22 of his 32 passes for 221 yards and a touchdown. Running back Raleek Brown also rushed 21 times or 80 yards. Leavitt also had a huge game on the ground rushing 15 times for 62 yards and a touchdown.
Arizona State on the season, is averaging 29.75 points while their defense is giving up 20.5 points per game. The offense is ranked 73rd in all of college football while the defense is ranked 56th. Having strong defense is going to be key in a big way here.
Why the Arizona State Sun Devils will win
- Arizona State has won each of its last eight games at Mountain America Stadium.
- Arizona State has covered the spread in nine of its last 10 games against conference opponents.
TCU Offense Continues to Impress
The TCU offense has been impressive all season, and they have a ton of confidence heading into this game. In the first game against North Carolina, they scored 48 points. In the last game against SMU they didn’t pull away big, but they were still able to secure the 35-24 victory. No one has been able to slow down Josh Hoover and he completed 22 of his 40 passes for 379 yards, five touchdowns and one interception. Eric McAlister also had one of the best games in team history finishing with eight catches for 254 yards and three touchdowns. The passing game is the clear strength of this team.
TCU on the season is averaging 41.67 points while their defense is giving up 19.67 points per game. The offense is ranked 23rd in college football while the defense is ranked 50th. The offense gets the attention, but the defense also looks like it might be better than the last couple of years.
Why the TCU Horned Frogs will win
- TCU has won each of its last seven games against non-AP-ranked teams.
- TCU has covered the spread in six of its last seven games against non-AP-ranked teams.
Arizona State vs TCU Prediction
Give me the over in this game, and give it to me in a big way. Arizona State’s defense isn’t good enough, and they don’t have the talent to slow down Hoover. In his last game he threw for 379 yards and five touchdowns. Is he going to reach 379 yards and five touchdowns again? I’m not sure about that, but he’s going to get close. The defense might be better for TCU, but they still aren’t going to be elite, and Arizona State is going to have no issue moving the ball. This is going to be a battle between two really good quarterbacks, and it’s going to be blow for blow with zero defense. Back the over to cash.