Buffalo vs Central Michigan Prediction 11/12/25 College Football Picks Today

In this article, we will formulate a Buffalo vs Central Michigan Prediction for this College Football Week 12 game on Wednesday, November 12^th. Let’s take a look at the prediction for this College Football matchup.

Central Michigan Chippewas Preview

Central Michigan has a 5-4 record this season and is sitting 3rd in the MAC. They are 6-3 ATS, 6-3 in Over/Under and have a 3-0 home record and a 2-4 away record. Central Michigan is coming off a 21-24 road loss against Western Michigan and will face Kent State next.

Offensively, Central Michigan averages 24.1 points per game, ranking 94th in the nation, while defensively, they allow 24.0 points per game, which is 60th. Central Michigan averages 338.9 total yards per game (153.6 passing and 185.3 rushing), while allowing 357.8 total yards per game (154.1 rushing and 203.7 passing).

Joey Labas leads Central Michigan with 1,066 passing yards with 71.6% completed passes and 8 touchdowns. Nahree Biggins leads the team in rushing yards with 426, while Langston Lewis has a team-high 21 receptions for 295 receiving yards. Defensively, Jordan Kwiatkowski has a team-high 73 total tackles (29 of them solo), while Michael Heldman leads the team in sacks, with 5.5.

Buffalo Bulls Preview

Buffalo has a 5-4 record this season and is sitting 2nd in the MAC. They are 3-5-1 ATS, 4-5 in Over/Under and have a 2-3 home record and a 3-1 away record. Buffalo is coming off a 28-3 road win against Bowling Green and will face Ohio next.

Offensively, Buffalo averages 24.8 points per game, ranking 88th in the nation, while defensively, they allow 19.6 points per game, which is 23rd. Buffalo averages 357.0 total yards per game (212.6 passing and 144.4 rushing), while allowing 323.6 total yards per game (139.3 rushing and 184.2 passing).

Ta’Quan Roberson leads Buffalo with 1,739 passing yards with 60.5% completed passes and 12 touchdowns. Al-Jay Henderson leads the team in rushing yards with 663, while Nik McMillan has a team-high 42 receptions for 590 receiving yards. Defensively, Khalil Murdock has a team-high 105 total tackles (38 of them solo), while Khalil Murdock leads the team in sacks, with 4.5. Jalen McNair, Mitchell Gonser, Oliver Bridges have one interception each.

Buffalo Bulls @ Central Michigan Chippewas Betting Trends: Week 12

Central Michigan Chippewas Player Prop Facts

• Heading into Week 12, Angel Flores ranks T2nd in the Mid-American Conference for rushing touchdowns (8) this season.

Buffalo Bulls Player Prop Facts

• Heading into Week 12, Nik McMillan is one of only three players in the FBS to record 100+ receiving yards in three or more consecutive games this season.

Matchup/League Facts

• Central Michigan ranks 135th among FBS teams for Q4 points per game this season (2.4).
• Central Michigan ranks 127th among FBS teams for H2 points per game this season (7.8).
• Buffalo ranks 5th among FBS teams for Q1 opponent points per game this season (1.9).
• Buffalo ranks 9th among FBS teams for H1 opponent points per game this season (6.9).

Buffalo vs Central Michigan Prediction

In this Buffalo vs Central Michigan Prediction, Central Michigan is coming as -2.5 point home favorites, with the total set at 43.5 points. Both teams have identical overall record this season and both have excellent home/away splits, as Central Michigan has a 3-0 home record and Buffalo a 3-1 road record. Both teams have been very effective offensively lately, as Central Michigan has scored 21+ points in each of its last six games, while Buffalo has scored 28+ in three of its last four. Over is 4-1 in their last 5 meetings and I expect another high-scoring affair today, so take the over 43.5 points.