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BYU vs Iowa State Prediction 10/25/25 College Football Picks Today

BYU vs Iowa State
October 25, 2025 3:30 pm EDT
The Line: Iowa State -2.5 / Over/Under: 49
(Get latest betting odds)

In this article, we will formulate a BYU vs Iowa State Prediction for this College Football Week 9 game on Saturday, October 25th. Let’s take a look at the prediction for this College Football matchup.

Iowa State Cyclones Preview

Iowa State has a 5-2 record this season and is sitting 6th in the Big 12. They are 3-3-1 ATS, 3-4 in Over/Under and have a 3-0 home record and a 1-2 away record. Iowa State is coming off a 17-24 road loss against Colorado and will face Arizona State, Texas Christian and Kansas next.

Offensively, Iowa State averages 29.3 points per game, ranking 67th in the nation, while defensively, they allow 19.0 points per game, which is 28th. Iowa State averages 406 total yards per game (242.1 passing and 163.9 rushing), while allowing 345.3 total yards per game (141.6 rushing and 203.7 passing).

Rocco Becht leads Iowa State with 1,622 passing yards with 63.2% completed passes and 9 touchdowns. Abu Sama leads the team in rushing yards with 481, while Benjamin Brahmer has a team-high 24 receptions for 242 receiving yards. Defensively, Marcus Neal has a team-high 45 total tackles (27 of them solo), while Marcus Neal leads the team in sacks, with 1.0, and Jamison Patton has a team-high 2 interceptions.

BYU Cougars Preview

BYU has a 7-0 record this season and is sitting 1st in the Big 12. They are 5-2 ATS, 3-4 in Over/Under and have a 4-0 home record and a 3-0 away record. BYU is coming off a 24-21 home win against Utah and will face Texas Tech, Texas Christian and Cincinnati next.

Offensively, BYU averages 35.6 points per game, ranking 30th in the nation, while defensively, they allow 15.6 points per game, which is 14th. BYU averages 436.7 total yards per game (203.9 passing and 232.9 rushing), while allowing 293.0 total yards per game (121.6 rushing and 171.4 passing).

Bear Bachmeier leads BYU with 1,386 passing yards with 62.7% completed passes and 9 touchdowns. LJ Martin leads the team in rushing yards with 774, while Chase Roberts has a team-high 24 receptions for 463 receiving yards. Defensively, Faletau Satuala has a team-high 43 total tackles (26 of them solo), while Jack Kelly leads the team in sacks, with 5.0, and Tanner Wall has a team-high 2 interceptions.

BYU Cougars @ Iowa State Cyclones Betting Trends: Week 9

 

Why the Iowa State Cyclones will win

  • Iowa State has won four of its last five October games against top-15 AP-ranked teams.
  • The home team has covered the spread in each of Iowa State’s last four games.
  • Iowa State has won the first half in three of its last four home games against conference opponents.

Why the BYU Cougars will win

  • BYU has won each of its last nine games.
  • Iowa State has lost four of its last five games as a favorite against AP-ranked teams.
  • Iowa State has failed to cover the spread in 10 of its last 11 games against top-15 AP-ranked teams.
  • BYU has covered the spread in eight of its last nine games as an underdog.

Total Points Facts

  • Each of BYU’s last five October games against non-AP-ranked teams have gone OVER the total points line.
  • Each of Iowa State’s last four games against top-15 AP-ranked teams at Jack Trice Stadium have gone UNDER the total points line.

Iowa State Cyclones Player Prop Facts

  • Heading into Week 9, Rocco Becht leads Iowa State for touchdowns (7) this season.

BYU Cougars Player Prop Facts

  • Heading into Week 9, LJ Martin leads the Big 12 Conference for rush attempts (127) this season.

Matchup/League Facts

  • Iowa State has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
  • Iowa State ranks 10th among FBS teams for 4th down conversion percentage against this season (31.3).
  • BYU has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
  • BYU ranks T4th among FBS teams for average point differential in second quarters this season (+8.1).

BYU vs Iowa State Prediction

In their only previous meeting in 2023, Iowa State won 45-13 on the road, covering the spread, as the game went over the point total.

In this BYU vs Iowa State Prediction, Iowa State is coming as -2.5-point home favorites, with the total set at 49 points. Iowa State has back-to-back losses after winning its first 5 games of the season, while on the flip side, BYU has been undefeated in its seven games played. The Cougars are better both offensively and defensively and have been winning by an average of 20 points this season. The wrong team is favored in this matchup, so take the plus money with the road dog. Take BYU on the moneyline in this one.

Nikos Lagouretos's Free Pick: BYU ML

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