Colorado vs Arizona Prediction Football Picks Today 11/1/25

In this article we will formulate a Colorado vs Arizona prediction for this College Football game on Saturday, November 1st at Folsom Field in Boulder, Colorado. Let’s take a look at the prediction for this week 10 matchup. 

Colorado Buffaloes Betting Preview

The Colorado Buffaloes are 3-5 (1-4) this year after they lost to Utah by a score of 53-7 last week. Colorado trailed 43-0 at halftime and they were blown out, but they did score in the fourth quarter to avoid the shutout. The Buffaloes were out gained by a total of 587-140, went 3-16 on third downs, and lost the turnover battle by a total of 1-0 in the game. Kaidon Salter went 9-22 for 37 yards and one interception, while Kam Mikell rushed eight times for 44 yards. Omarion Miller led the receivers with three receptions for 59 yards in the loss. The Colorado defense recorded one sack and five tackles for loss in the game. 

Prior to that game, Colorado defeated Iowa State by a score of 24-17, but did lose to TCU by a score of 35-21 before that. The Buffaloes have lost three of their last four games and they are currently near the bottom of the Big 12 standings. Colorado has scored 22.6 points per game with 203.5 passing yards and 130.1 rushing yards per game, while they have allowed 27.4 points against per game this season. Kaidon Salter has thrown for 1,193 yards, nine touchdowns, and five interceptions, while Omarion Miller has 23 receptions for 430 yards and four scores this year. 

Arizona Wildcats Betting Preview

The Arizona Wildcats are 4-3 (1-3) this season after they lost to Houston by a score of 31-28 in their last game. Arizona trailed 21-14 at halftime, but they tied the game at 28 in the fourth, before losing on a last second field goal. The Wildcats were out gained by a total of 396-381, went 4-9 on third downs, and tied the turnover battle at zero in the game. Noah Fifita went 24-26 for 269 yards and two touchdowns, while Ismail Mahdi rushed six times for 42 yards. Tre Spivey led the receivers with one reception for 70 yards in the loss. The Arizona defense recorded zero sacks and two tackles for loss in the game. 

Prior to that game, Arizona lost to BYU by a score of 33-27, but did beat Oklahoma State by a score of 41-13 before that. The Wildcats have lost three of their last four games and they are currently a half game better than Colorado in the Big 12 standings. Arizona has scored 31.6 points per game with 274.1 passing yards and 142.1 rushing yards per game, while they have allowed 20.3 points against per game this season. Noah Fifita has thrown for 1,829 yards, 17 touchdowns, and four interceptions, while Ismail Mahdi has rushed for 445 yards and one score on 77 carries this season. 

Why the Colorado Buffaloes will win

• Colorado has won each of its last nine November home games against non-AP-ranked teams.
• Arizona has lost each of its last five road games.
• Colorado has covered the spread in each of its last nine games against conference opponents at Folsom Field.
• Arizona has failed to cover the spread in seven of its last eight November road games against non-AP-ranked teams.
• Colorado has won the first quarter in seven of its last eight games against conference opponents at Folsom Field.
• Arizona has lost the first half in each of its last five road games against conference opponents.

Total Points Facts

• Nine of Colorado’s last 10 games as an underdog against teams from Arizona have gone OVER the total points line.
• Each of Arizona’s last five road games have gone OVER the total points line.

Matchup/League Facts

• Colorado ranks 134th among FBS teams for rushing yards allowed per game this season (217.3).
• Colorado ranks T123rd among FBS teams for 1st downs against this season (184).
• Arizona ranks T7th among FBS teams for Q1 points per game this season (10.4).
• Arizona ranks 9th among FBS teams for passing yards allowed per game this season (153.1).

Colorado vs Arizona Prediction 

Colorado limps into this matchup after getting blown out last week against Utah, but they will be back at home, where they just beat Iowa State two games ago. Arizona is coming off of two very tough losses, one of which was in overtime and the other was a last second field goal, and they have allowed 31+ in three of their last four games. Neither team is very good in this matchup, but Colorado plays much better at home and this Arizona defense is simply not good. Take Colorado and the points here. 

David Racey is 93-72 (57%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!