Delaware vs Vanderbilt Prediction Football Picks Today 9/12/26
Delaware Blue Hens (1-0) vs. Vanderbilt Commodores (1-0)
September 12, 2026 4:15 pm EDT
The Line: Vanderbilt Commodores -1350 / Delaware Blue Hens 800; Over/Under: 54.5
(Get latest betting odds)
In this article, we will formulate a Delaware vs Vanderbilt Prediction for this College Football Week 2 matchup on Saturday, September 12th. Let’s take a look at the prediction for this College Football matchup.
Vanderbilt Preview
The Commodores have a 1-0 record and are coming off a 28-9 victory over Austin Peay, where they outgained them 395-178 yards. Vanderbilt had 209 passing yards, 186 rushing yards, and 18/25 completed passes. They were 4/12 on third down conversions, had 9-73 penalties, and the turnover battle was tied at 0-0.
Blaze Berlowitz led Vanderbilt with 11/16 passes and 149 passing yards. Sedrick Alexander had a team-high 60 rushing yards, while Junior Sherrill caught 4 passes for a team-high 70 receiving yards. Defensively, Nick Rinaldi and CJ Heard led the Commodores with 6 total tackles each, and Issa Ouattara led the team with 2 sacks.
Delaware Preview
The Blue Hens have a 1-0 record and are coming off a 42-7 home win over Merrimack, where they outgained their opponents 547-244 yards. Delaware had 435 passing yards, 112 rushing yards, and 24/44 completed passes. They were 6/13 on third down conversions, had 4-45 penalties, and won the turnover battle by 1-2.
Nicholas Minicucci led Delaware with 20/36 passes and 330 passing yards. NaKeem Powell had a team-high 35 rushing yards, while Kaderris Roberts caught 2 passes for a team-high 80 receiving yards. Defensively, Noah Jefferson led the Blue Hens with 8 total tackles, 3 of them solo, and Blake Matthews led the team with one sack.
Delaware Blue Hens @ Vanderbilt Commodores Betting Trends: Week 2
Why the Vanderbilt Commodores will win
- Vanderbilt has won each of its last nine games against non-conference opponents at FirstBank Stadium.
- Delaware has lost each of its last four road games.
- Vanderbilt has covered the spread in each of its last six games against opponents from the Conference USA.
- Delaware has failed to cover the spread in each of its last four road games.
- Vanderbilt has won the first half in each of its last nine games against non-conference opponents at FirstBank Stadium.
Why the Delaware Blue Hens will win
- Delaware has won four of its last six games as an underdog.
- Vanderbilt has failed to cover the spread in 14 of its last 16 home games in September.
- Delaware has covered the spread in each of its last three games.
- Delaware has won the first half in each of its last three games.
- Delaware has won the first quarter in three of its last four games against non-conference opponents.
Total Points Facts
- Twelve of Vanderbilt’s last 13 September games against non-AP-ranked teams have gone OVER the total points line.
- Three of Delaware’s last four road games have gone OVER the total points line.
Vanderbilt Commodores Player Prop Facts
- Heading into Week 2, Kayleb Barnett ranks T1st amongst qualified players for catch rate (100.0%) this season.
Delaware Blue Hens Player Prop Facts
- Heading into Week 2, Kaderris Roberts ranks T1st amongst qualified players for catch rate (100.0%) this season.
Matchup/League Facts
- Vanderbilt ranks T1st among FBS teams for Q3 opponent points per game this season (0.0).
- Vanderbilt ranks T1st among FBS teams for Q4 opponent points per game this season (0.0).
- Delaware ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
- Delaware ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
Delaware vs Vanderbilt Prediction
Both teams are coming off big wins in their season openers, winning by 35 and 19 points respectively. Both defensively lines good great as they held their opponents into just 16 games combined and as a result, both games went under the total. Vanderbilt was excellent against the spread last season with a 10-3 record and were 4-1 ATS in their last 5 home games, while Delaware struggling against the spread with a 5-8 ATS record. It is a big number, but I trust the hosts to win this one comfortably and cover the -21.5.