Duke vs Connecticut Prediction 11/8/25 College Football Picks Today
Duke vs Connecticut
November 8, 2025 3:30 pm EDT
The Line: Duke -9 / Over/Under: 65.5
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In this article, we will formulate a Duke vs Connecticut Prediction for this College Football Week 11 game on Saturday, November 8th. Let’s take a look at the prediction for this College Football matchup.
Connecticut Huskies Preview
Connecticut has a 6-3 record this season and is sitting second in the Ind. They are 4-3 ATS, 6-3 in Over/Under and have a 4-0 home record and a 2-3 away record. Connecticut is coming off a 38-19 home win against UAB and will face Air Force and Florida Atlantic next.
Offensively, Connecticut averages 36.9 points per game, ranking 15th in the nation, while defensively, they allow 23.9 points per game, which is 63rd. Connecticut averages 455.6 total yards per game (299.3 passing and 156.2 rushing), while allowing 391.7 total yards per game (175.0 rushing and 216.7 passing).
Joe Fagnano leads Connecticut with 2,529 passing yards with 68.8% completed passes and 22 touchdowns. Camryn Edwards leads the team in rushing yards with 815, while Skyler Bell has a team-high 74 receptions for 994 receiving yards. Defensively, Byrun Parham has a team-high 80 total tackles (40 of them solo), while Byrun Parham leads the team in sacks, with 9.5, and Cam Chadwick has a team-high 4 interceptions.
Duke Blue Devils Preview
Duke has a 5-3 record this season and is sitting 5th in the ACC. They are 4-4 ATS, 6-2 in Over/Under and have a 2-2 home record and a 3-1 away record. Duke is coming off a 46-45 road win against Clemson and will face Virginia, North Carolina and Wake Forest next.
Offensively, Duke averages 35.4 points per game, ranking 25th in the nation, while defensively, they allow 28.1 points per game, which is 95th. Duke averages 460.3 total yards per game (324.3 passing and 136.0 rushing), while allowing 398.9 total yards per game (135.6 rushing and 263.3 passing).
Darian Mensah leads Duke with 2,572 passing yards with 69.7% completed passes and 21 touchdowns. Nate Sheppard leads the team in rushing yards with 557, while Cooper Barkate has a team-high 45 receptions for 774 receiving yards. Defensively, Caleb Weaver has a team-high 57 total tackles (20 of them solo), while Vincent Anthony Jr. leads the team in sacks, with 6.5, and Moussa Kane has a team-high 2 interceptions.
Duke Blue Devils @ Connecticut Huskies Betting Trends: Week 11
Why the Connecticut Huskies will win
- Connecticut has won each of its last six home games.
- Duke has lost three of its last four games against non-conference opponents.
- Duke has failed to cover the spread in each of its last four games against non-conference opponents.
- Connecticut has covered the spread in six of its last seven home games in November.
- Connecticut has won the first quarter in each of its last five home games against non-conference opponents.
- Connecticut has won the first half in each of its last five home games against non-conference opponents.
Why the Duke Blue Devils will win
- The favorite has won each of Connecticut’s last 15 games at Pratt & Whitney Stadium at Rentschler Field.
- Connecticut has lost 19 of its last 20 November games as an underdog against non-AP-ranked teams.
- Duke has covered the spread in each of its last five November games against non-AP-ranked teams.
- Connecticut has failed to cover the spread in three of its last four games as a home underdog.
- Connecticut has lost the first half in 17 of its last 20 games against opponents from the Atlantic Coast Conference.
Total Points Facts
- Seven of Connecticut’s last eight November games as an underdog have gone OVER the total points line.
- Each of Duke’s last five games against non-conference opponents have gone OVER the total points line.
Connecticut Huskies Player Prop Facts
- Heading into Week 11, Skyler Bell ranks 1st amongst FBS players for receiving touchdowns (11) this season.
Duke Blue Devils Player Prop Facts
- Darian Mensah has recorded 250+ passing yards in eight consecutive games – longest streak in the FBS, heading into Week 11.
Matchup/League Facts
- Connecticut has suffered the equal-most road losses by a margin of 10 points or less of any FBS team this season (3).
- Connecticut has played in the equal-highest number of games that went to overtime this season (3).
- Duke ranks 4th among FBS teams for passing yards per game this season (324.3).
- Duke ranks T7th among FBS teams for Q4 points per game this season (10.3).
Duke vs Connecticut Prediction
In this Duke vs Connecticut Prediction, Duke is coming as -9-point road favorites, with the total set at 65.5 points. Both teams have almost identical overall record this season and are both in very good form lately, as they are 5-1 and 4-1 in their last 6 and 5 games respectively. Connecticut is better both offensively and defensively than Duke, as they have the 15th-best offense in the country and are winning by an average of 13 points per game. I like the hosts as home dogs in this spot, so take Connecticut and the +9 points in this one.