College Football

Duke vs Kansas 9/25/21 College Football Picks, Odds, Predictions

Kansas Jayhawks (1-2) vs. Duke Blue Devils (2-1)
September 25, 2021 4:00 pm EDT
The Line: Duke Blue Devils -15.5 / Kansas Jayhawks +15.5; Over/Under: 58
(Get latest betting odds)

The Duke Blue Devils meet the Kansas Jayhawks and Saturday in week 4 college football action at Wallace Wade Stadium in Durham. The Kansas Jayhawks need a bounce back win to get back to a .500 record. The Duke Blue Devils look for a third straight win to improve to 3-1 on the year.

The Kansas Jayhawks haven’t won a road game since September of 2019. Jason Bean is completing 56.1 percent of his passes for 409 yards, three touchdowns and zero interceptions. Kwamie Lassiter II and  Luke Grimm have combined for 211 receiving yards on 18 catches while Trevor Wilson has seven receptions. The Kansas Jayhawks ground game is averaging 130 yards per contest, and Bean leads the way with 221 yards and two touchdowns. Defensively, Kansas is allowing 36 points and 432.7 yards per game. Kenny Logan Jr. leads the Kansas Jayhawks with 23 tackles, Kyron Johnson has 1.5 sacks and O.J. Burroughs has one pass deflection.


The Duke Blue Devils have split their last six home games. Gunnar Holmberg is completing 71 percent of his passes for 812 yards, two touchdowns and one interceptions. Jake Bobo and Jalon Calhoun have combined for 435 receiving yards on 41 catches while Mataeo Durant has eight receptions. The Duke Blue Devils ground game is averaging 241.7 yards per contest, and Durant leads the way with 398 yards and seven touchdowns. Defensively, Duke is allowing 23.7 points and 383 yards per game. Shaka Heyward leads the Duke Blue Devils with 32 tackles, RJ Oben has one sack and Lummie Young IV has one interception. 

The Jayhawks are 20-43-1 ATS in their last 64 road games and 5-16 ATS in their last 21 games overall. The Blue Devils are 37-15-1 ATS in their last 53 non-conference games and 2-5 ATS in their last 7 games overall. The over is 16-5-1 in Jayhawks last 22 games overall. The over is 9-3 in Blue Devils last 12 games overall.

The Kansas Jayhawks are better than many give them credit for, as they have speed on offense and a good head coach. However, Kansas is still struggling to win or cover numbers and that’s all we care about in this business. Duke is 12-2-1 against the spread in its last 15 games as a double-digit favorite. Duke has a dominant offensive player in Mataeo Durant and is currently 13th in college football in total yards per game. Duke was kind to us last week against Northwestern. I’m riding the Blue Devils again.

Randy Chambers's Free Pick: Duke Blue Devils -15.5

Need More? Get Premium Picks

Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

Related Articles

Back to top button