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Eastern Michigan vs Central Michigan Prediction 9/27/25 College Football Picks Today

Eastern Michigan vs Central Michigan
September 27, 2025 1:00 pm EDT
The Line: Central Michigan -5.5 / Over/Under: 54
(Get latest betting odds)

In this article, we will formulate an Eastern Michigan vs Central Michigan Prediction for this College Football Week 5 game on Saturday, September 27th at the Kelly/Shorts Stadium. Let’s take a look at the prediction for this College Football matchup.

Central Michigan Preview

Central Michigan has a 2-2 record this season and are sitting on the 4th place of the Mid-American Conference. They are 2-2 ATS, 3-1 in Over/Under and have a 1-0 home record and 1-2 away record. The Chippewas are coming off a 49-10 home victory over Wagner and are playing Akron and Bowling Green next.

Offensively, the Chippewas average 21.2 points per game, which ranks 106th in the nation. Defensively, they allow 33.0 points per game, which is 123rd. Central Michigan averages 301.3 total yards per game, with 145.0 rushing yards and 156.3 passing yards per game. They allow 394.0 total yards per game, with 163.0 rushing and 231.0 passing yards per game.

Joey Labas leads the Chippewas with 422 passing yards and 69.6% completed passes. Trey Cornist leads the team in rushing yards, with 181, while Tommy McIntosh has a team-high 7 caught passes for 124 receiving yards, and has one touchdown. Defensively, Jordan Kwiatkowski has a team-high 24 total tackles, 13 of them solo. Michael Heldman leads the Chippewas in sacks, with 3, while Jordan Kwiatkowski has one interception.

Eastern Michigan Preview

Eastern Michigan has a 1-3 record this season and are sitting on the 9th place of the Mid-American Conference. They are 2-2 ATS, 3-1 in Over/Under and have a 1-1 home record and 0-2 away record. The Eagles are coming off a 34-31 home victory over Louisiana and are playing Central Michigan, Buffalo and Northern Illinois next.

Offensively, the Eagles average 26.8 points per game, which ranks 84th in the nation. Defensively, they allow 39.8 points per game, which is 132nd. Eastern Michigan averages 393.0 total yards per game, with 144.8 rushing yards and 248.3 passing yards per game. They allow 507.0 total yards per game, with 272.3 rushing and 234.8 passing yards per game.

Noah Kim leads the Eagles with 993 passing yards and 64.0% completed passes. Dontae McMillan leads the team in rushing yards, with 345, while Terry Lockett Jr. has a team-high 18 caught passes for 259 receiving yards, and has one touchdown. Defensively, Bryce Llewellyn has a team-high 29 total tackles, 6 of them solo. Messiah Blair leads the Eagles in sacks, with one, while Bryce Llewellyn has one interception.

Eastern Michigan Eagles @ Central Michigan Chippewas Betting Trends: Week 5

 

Why the Central Michigan Chippewas will win

  • Central Michigan has won each of its last six home games against Eastern Michigan.
  • Eastern Michigan has lost eight of its last nine games.
  • Central Michigan has covered the spread in each of its last four home games.
  • Eastern Michigan has failed to cover the spread in four of its last five road games.
  • Eastern Michigan has lost the first half in four of its last five games against conference opponents.

Why the Eastern Michigan Eagles will win

  • Central Michigan has lost six of its last seven games against conference opponents.
  • Central Michigan has failed to cover the spread in seven of its last eight games against teams from Michigan.
  • Eastern Michigan has covered the spread in seven of its last eight games in September.
  • Central Michigan has lost the first half in six of its last seven games against conference opponents.

Total Points Facts

  • Seven of Eastern Michigan’s last eight games as an underdog in Michigan have gone OVER the total points line.
  • Five of Central Michigan’s last six September games as a favorite have gone OVER the total points line.

Central Michigan Chippewas Player Prop Facts

  • Heading into Week 5, Joe Labas has recorded the longest passing touchdown in a single game this season (88 yards vs Wagner Seahawks, Week 4).

Eastern Michigan Eagles Player Prop Facts

  • Heading into Week 5, Ben Prosper ranks T1st amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

  • Central Michigan has suffered the equal-most road losses by a margin of 25+ points of any FBS team this season (2).
  • Central Michigan ranks T133rd among FBS teams for Q4 points per game this season (0.8).
  • Eastern Michigan ranks 136th among FBS teams for rushing yards allowed per game this season (272.3).
  • Eastern Michigan ranks T1st among FBS teams for red zone percentage this season (100.0).

Eastern Michigan vs Central Michigan Prediction

In their previous meeting last season, Eastern Michigan won 38-34 at home. Central Michigan is 4-2 in their last 6 meetings against Eastern Michigan, and have won their last five home meetings against the Eagles. Their last three meetings have gone over the total.

In this Eastern Michigan vs Central Michigan Prediction, Central Michigan is coming as -5.5-point home favorites, with the total set at 54 points. Both taems are coming off wins that ended their previous losing streaks, but I don’t trust Eastern Michigan on the road. Central Michigan is playing their second straight home game, after winning and covering the spread at home in the previous week, and they have been dominating the Eagles at home in recent years. Take Central Michigan and lay the -5.5 points in this one.

Nikos Lagouretos's Free Pick: Central Michigan -5.5

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