Florida vs LSU Prediction 9/13/25 College Football Picks Today

In this article, we will formulate a Florida vs LSU Prediction for this College Football Week 3 game on Saturday, September 13^th at the Tiger Stadium (LA). Let’s take a look at the prediction for this College Football matchup.

LSU Tigers Preview

The Tigers have a 2-0 record this season and are ranked as No.3 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Tigers are coming off a 23-7 home victory over Louisiana Tech. LSU outgained their opponents by 365-154 yards. They had 26/41 completed passes, 237 passing yards, 128 rushing yards, with turnovers being 1-0. The Tigers went 9-16 in third down efficiency and had 9-77 penalties.

Garrett Nussmeier had 26/41 passes, a team-high 237 passing yards, one touchdown and one interception. Harlem Berry added a team-high 56 rushing yards, while Barion Brown caught 8 passes for 94 yards. Defensively, West Weeks had 10 total tackles, four of them solo, while West Weeks, Jack Pyburn, Whit Weeks and Jardin Gilbert each recorded 0.5 sacks. The Tigers did not record any interceptions in this game.

Florida Gators Preview

The Gators have a 1-1 record this season and are ranked as No.11 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Gators are coming off a 16-18 home defeat by South Florida. Florida outgained their opponents by 355-391 yards. They had 23/33 completed passes, 222 passing yards, 133 rushing yards, with turnovers being 1-0. The Gators went 4-12 in third down efficiency and had 11-103 penalties.

DJ Lagway had 23/33 passes, a team-high 222 passing yards, one touchdown and one interception. Jadan Baugh added a team-high 93 rushing yards, while Eugene Wilson III caught 7 passes for 60 yards. Defensively, Jaden Robinson had 9 total tackles, four of them solo, while Tyreak Sapp recorded 1 sack. The Gators did not record any interceptions in this game.

Florida vs LSU Prediction

In their previous meeting last season, Florida won 27-16 at home, covering the spread, as the game went under the point total. LSU is 5-1 in their last 6 head-to-head meetings, having won their last three home meetings against Florida. LSU is 5-1 against the spread in their last 6 meetings, and over is 6-1 in their last 7 meetings.

In this Florida vs LSU Prediction, LSU is coming in as -7.5-point home favorites, with the total set at 48.5 points. Both teams are coming off opposite outcomes in their previous games, and LSU has been undefeated in their two games this season, playing elite defense, holding their opponents into just 8.5 points per game. Florida has also been efficient defensively, allowing 9 points per game, and both teams are 4-0 to the under in their first four games of the season combined. I expect another low-scoring affair between two strong defenses, so take the under 48.5 points in this one.

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