Indiana vs UCLA Prediction Football Picks Today 10/25/25

The UCLA Bruins and the Indiana Hoosiers meet in week 9 college football action from Memorial Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a UCLA Bruins vs. Indiana Hoosiers prediction.

UCLA Bruins Recap

The UCLA Bruins come into this game looking to add on to their 20-17 win over Maryland last time out to improve to 3-4 this season. After this game, UCLA will head for a bye week before taking on Nebraska at home.

Bruins Win 3 Straight After 0-4 Start

Nico Iamaleava has thrown for 1,355 yards, 10 touchdowns and 5 interceptions on 65.2% passing while also leading UCLA in rushing with 360 yards and 4 TDs on the ground. Jalen Berger, Jaivian Thomas and Anthony Woods all have 200+ rushing yards this season while Kwazi Gilmer has a team-high 30 catches for 369 yards and 2 TDs. Titus Mokiao-Atimalala has 240 receiving yards and Mikey Matthews has 205 receiving yards while another pair of Bruins have 100+ receiving yards as well this season. On defense, JonJon Vaughns has a team-high 66 total tackles while the Bruins’ defense as a unit has combined for 6 sacks and an interception so far this season.

Why the UCLA Bruins will win

• UCLA has won each of its last three October games as an underdog.
• The team ranked 2nd in the AP Poll has failed to cover the spread in each of its last six games.
• The underdog has covered the spread in each of UCLA’s last six games.

Indiana Hoosiers Recap

The Indiana Hoosiers will be out to add on to their 38-13 win over Michigan State last time out to improve to 7-0 this season. After this game, Indiana will head on the road for a game against Maryland.

Hoosiers Looking To Remain Unbeaten

Fernando Mendoza has thrown for 1,755 yards, 21 touchdowns and 2 interceptions on 73.5% passing while Kaelon Black leads Indiana on the ground with 439 rushing yards with 3 TDs and Roman Hemby has 432 rushing yards and 2 TDs. Khobie Martin has 262 rushing yards with 4 TDs and Lee Beebe Jr. has 209 rushing yards as well on the year. Elijah Sarratt leads Indiana with 43 receptions for 603 yards and 9 TDs while Omar Cooper Jr. has 37 grabs for 581 yards and 7 touchdowns. E.J. Williams Jr. has 212 receiving yards while another pair of Hoosiers have 100+ receiving yards as well this season. On defense, Louis Moore has a team-high 49 total tackles while Isaiah Jones has a team-high 4.5 sacks and Mario Landino and Rolijah Hardy each have 4 sacks. The aforementioned Moore has a team-high 4 interceptions and Amare Farrell has 3 interceptions. As a unit, Indiana’s defense has combined for 26 sacks and 9 interceptions so far this season. 

Why the Indiana Hoosiers will win

• Indiana has won each of its last 16 games against non-AP-ranked teams.
• UCLA has lost each of its last 10 road games against top-15 AP-ranked teams.
• Indiana has covered the spread in five of its last six games in October.
• UCLA has failed to cover the spread in three of its last four road games against top-15 AP-ranked teams.

Total Points Facts

• Eight of UCLA’s last nine October games as an underdog against top-15 AP-ranked teams have gone OVER the total points line.
• Each of Indiana’s last four home games have gone OVER the total points line.

UCLA Bruins vs. Indiana Hoosiers Prediction

I’m on Indiana here. I get the case to be made for UCLA after rallying for some solid wins as of late and nearly getting back to .500, but I think this is a bad spot for the Bruins. The book is out on UCLA now as far as I’m concerned, to the point that Indiana is going to shut down anything funny UCLA tries and I just don’t see the Bruins getting any stops here. Give me Indiana in this one.