Indiana vs Western Kentucky Prediction Football Picks Today 9/19/26
Western Kentucky Hilltoppers (0-2) vs. Indiana Hoosiers (2-0)
September 19, 2026 4:00 pm EDT
The Line: Indiana Hoosiers -44.5 / Western Kentucky Hilltoppers +44.5; Over/Under: 60.5
(Get latest betting odds)
The Western Kentucky Hilltoppers and the Indiana Hoosiers meet in week 3 college football action from Memorial Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Western Kentucky Hilltoppers vs. Indiana Hoosiers Prediction.
Western Kentucky Hilltoppers Recap
The Western Kentucky Hilltoppers come into this game looking to rebound from a 70-20 loss at the hands of Georgia last time out to sit at 0-2 this season. After this game, the Hilltoppers will head home for a game against Mercyhurst.
WKU Looking For Monumental Upset
Rodney Tisdale Jr. has thrown for 234 yards, 0 touchdowns and 1 interception on 55.6% passing while Ajay Allen leads the Hilltoppers in rushing with 121 rushing yards and 2 touchdowns so far this season. Zero more Hilltoppers have at least 100 rushing yards as well this season including Brock Glenn who has 70 yards and 2 TDs while Cameron Flowers leads Western Kentucky in receiving with 74 receiving yards and 8 catches to lead Western Kentucky along with 0 touchdowns as well this season. On defense, Jaylen Lewis has a team-high 13 total tackles in addition to 0 sacks while Western Kentucky’s defense as a whole has combined for 0 sacks and 1 interception so far this season.
Indiana Hoosiers Recap
The Indiana Hoosiers come into this game looking to add on to their 55-0 win over Howard last time out to sit at 2-0 this season. After this game, Indiana will take on the Northwestern Wildcats at home.
Hoosiers Looking To Stay Unbeaten Ahead Of Big Ten Play
Josh Hoover has thrown for 376 yards, 8 touchdowns and 0 interceptions on 70.4% passing while Turbo Richard leads the Hoosiers in rushing with 166 rushing yards and 3 touchdowns so far this season. One more Hoosier has at least 100 rushing yards as well this season including Lee Beebe Jr. who has 145 yards and 0 TDs while Charlie Becker leads Indiana in receiving with 145 receiving yards and 7 catches to lead Indiana along with 5 touchdowns as well this season. On defense, Isaiah Jones has a team-high 17 total tackles in addition to 0 sacks while Indiana’s defense as a whole has combined for 6 sacks and 2 interceptions so far this season.
Western Kentucky Hilltoppers @ Indiana Hoosiers Betting Trends: Week 3
Why the Indiana Hoosiers will win
- Indiana has won each of its last 23 games against non-AP-ranked teams.
- Western Kentucky has lost each of its last eight games against AP-ranked teams.
- Western Kentucky has failed to cover the spread in each of its last four games against AP-ranked teams.
- Indiana has covered the spread in six of its last eight September games at Memorial Stadium (Bloomington).
- Indiana has won the first quarter in each of its last 11 games against non-AP-ranked teams.
- Indiana has won the first half in each of its last 17 games at Memorial Stadium (Bloomington).
Why the Western Kentucky Hilltoppers will win
- The team ranked 4th in the AP Poll has failed to cover the spread in five of its last six games.
- Western Kentucky has covered the spread in each of its last three games against teams from Indiana.
Total Points Facts
- Nine of Indiana’s last 10 September games at Memorial Stadium (Bloomington) have gone OVER the total points line.
- Each of Western Kentucky’s last four games against opponents from the Big Ten Conference have gone OVER the total points line.
Indiana Hoosiers Player Prop Facts
- Heading into Week 3, Charlie Becker ranks T1st amongst FBS players for receiving touchdowns (5) this season.
Western Kentucky Hilltoppers Player Prop Facts
- Heading into Week 3, Rodney Tisdale Jr. has the most pass attempts without a passing touchdown this season (54).
Matchup/League Facts
- Indiana ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
- Indiana ranks T1st among FBS teams for Q4 opponent points per game this season (0.0).
- Western Kentucky ranks 138th among FBS teams for points allowed per game this season (59.5).
- Western Kentucky ranks 138th among FBS teams for Q1 opponent points per game this season (17.5).
Western Kentucky Hilltoppers vs. Indiana Hoosiers Prediction
I’m on the Hoosiers in a blowout here. WKU is one of those teams this season that just schedules up for the paycheck but it could serve them better down the road in CUSA play when they’re up against teams more their speed. But for now, this is a mismatch of epic proportions, as WKU just doesn’t have the QB pop that they’ve had in past seasons and while Indiana’s played with their food a bit early on this year, I think the Hoosiers blow out Western Kentucky here.