Iowa vs Iowa State
September 6, 2025 12:00 pm EDT
The Line: Iowa State -3 / Over/Under: 41.5
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In this article, we will formulate an Iowa vs Iowa State Prediction for this College Football Week 2 game on Saturday, September 6th at the Jack Trice Stadium. Let’s take a look at the prediction for this College Football matchup.
Iowa State Cyclones Preview
The Cyclones are coming off a 55-7 home victory over South Dakota in their previous game, and are a perfect 2-0 this season. Iowa State outgained their opponents by 529-208 yards. They had 23/25 completed passes, 306 passing yards, 223 rushing yards, with turnovers being 0-2. The Cyclones went 9-10 in third down efficiency and had 3-30 penalties.
Rocco Becht had 19/20 passes, a team-high 278 passing yards and three touchdowns. Abu Sama III added a team-high 68 rushing yards, while Jayden Higgins caught 6 passes for 123 yards and one touchdown. Defensively, Caleb Bacon had nine total tackles, three of them solo, while Tyler Onyedim had one sack. Myles Purchase had one interception returned for 17 yards.
Iowa Hawkeyes Preview
The Hawkeyes are coming off a 34-7 home victory over Albany in their season opener. Iowa outgained their opponents by 358-177 yards. They had 9/16 completed passes, 48 passing yards, 310 rushing yards, with turnovers being 1-0. The Hawkeyes went 10-16 in third down efficiency and had 2-20 penalties.
Mark Gronowski had 8/15 passes, a team-high 44 passing yards and one touchdown. Kamari Moulton added a team-high 122 rushing yards and one touchdown, while Jacob Gill caught 1 pass for 13 yards. Defensively, Jayden Harrell had six total tackles, five of them solo, while Max Llewellyn had one sack. Sebastian Castro had one interception returned for 25 yards.
Iowa vs Iowa State Prediction
In their previous meeting last season, Iowa State won 20-19 on the road, not covering the spread, as the game went over the point total. Iowa is 7-2 in their last 9 head-to-head meetings, but both teams are 4-4 against the spread in their last 8 meetings. Under is 7-2-1 in their last 10 meetings.
In this Iowa vs Iowa State Prediction, Iowa State is coming in as -3.5-point home favorites, with the total set at 41.5 points. Both teams are coming off dominating victories in their previous games, as they won by 48 and 27 points respectively. The Cyclones were almost perfect at home last season with a 6-1 record, and even though they are dominated by the Hawkeyes at their home court, this it the team were this trend ends. The Cyclones looked far better in their win over South Dakota and have an extra game under their belt. Take the Iowa State Cyclones and lay the points at home.
