Iowa vs Oregon Prediction Football Picks Today 11/8/25

The Oregon Ducks and the Iowa Hawkeyes meet Saturday in college football action from Kinnick Stadium. Here’s an Iowa vs Oregon prediction. We will look at this from a betting perspective and determine the best Iowa vs Oregon pick.

Oregon Ducks Betting Preview

Oregon has been flexing their muscles for most of the year, and they kicked things off on a nice run. The Ducks opened with wins over Montana State, Oklahoma State, NOrthwestern, Oregon State and Penn State before a 10-point loss at home thanks to Indiana. Oregon was able to recover in the next game though, blowing out Rutgers in a road matchup. In the 56-10 win over the Knights, the Ducks posted a whopping 750 yards of offense with 415 rush yards, 12.5 yards per play, 29 first downs and 8-of-11 on third-down tries—but did have three turnovers. The defense had three takeaways to counteract the mistakes, though.

In their last matchup on October 25 versus Wisconsin, the Ducks were up 14-0 going into the final quarter. Oregon was able to exchange touchdowns in that last frame on the way to a 21-7 victory at home. QB Dante Moore finished with a 9-of-15 line for 86 yards, and Jordon Davison managed 16 carries for 102 yards and two touchdowns. Dakorien Moore was the team’s leading receiver with three grabs for 45 yards in the win.

Iowa Hawkeyes Betting Preview

Over on the Iowa side, they got off to a pretty solid start at 3-1. The lone loss in that time was versus Iowa State; otherwise it was wins over Albany, UMass and Rutgers. Following a close loss to Indiana at home on September 27, the Hawkeyes rattled off wins over Wisconsin and Penn State in the next pair. In the win over the Nittany Lions on October 18, the Hawkeyes ended up with 313 offensive yards, but just 68 of those came through the air. Iowa had 6.4 yards per play in the win but also just 11 first downs and 4-of-10 on third-down tries. The defense held Penn State to just 266 yards and had two interceptions, though.

Iowa last played on October 25 versus Minnesota. In that game the Hawkeyes jumped out to a comfortable 31-0 halftime lead, scoring in every quarter on the way to a blowout home win 41-3. QB Mark Gronowski went 12-of-19 for 135 yards and a score while Kamari Moulton had 75 yards on 15 carries. Gronowski also had a rush TD, and leading receiver Kaden Wetjen had three grabs for 49 yards in the victory effort.

Iowa vs Oregon Prediction

I’ll stick with Iowa, but this is obviously going to be a tough one; the line’s really thin. I’d like to see a little more pizzaz from the offense this time, as the Hawkeyes had just 13 first downs and a 4-of-12 success rate on third-down conversion attempts in their blowout win over Minnesota. Iowa really looked great on defense though, posting 133 yards, 2.5 yards per play, 10 first downs and 4-of-13 on third-down tries allowed alongside three picks. That gives Iowa 25 or more points in three straight victories, with two of those being utter blowout finishes.

As for Oregon, they looked pretty darn good on defense themselves in their win over Wisconsin. The Ducks held the Badgers to just 196 yards, 3.9 yards per play, 11 first downs and 3-of-11 on third-down tries. Oregon has scored 21 or fewer points in two of their last three outings though, so they could be ripe for a defensive stifling at the hands of the Hawkeyes. I like this one to be one of the more intriguing matchups of the weekend, and I think Iowa can power one out cover-wise. Should be a great game.