College Football

Kansas vs Missouri Prediction Football Picks Today 9/11/26

Missouri Tigers (1-0) vs. Kansas Jayhawks (1-0)
September 11, 2026 8:00 pm EDT
The Line: Kansas Jayhawks 5.5 / Missouri Tigers -5.5; Over/Under: 51.5
(Get latest betting odds)

The Missouri Tigers and Kansas Jayhawks meet Friday in week 2 college football action at Memorial Stadium. Here’s a Kansas vs Missouri Prediction. This article will include a Kansas vs Missouri Pick.

Missouri Tigers Betting Preview

The Missouri Tigers beat Arkansas-Pine Bluff, and they play Troy next. The Missouri Tigers look to start 2-0 for a fourth straight season. Austin Simmons is completing 89.5 percent of his passes for 252 yards, 4 touchdowns, and 0 interceptions. Donovan Olugbode and Cayden Lee have combined for 196 receiving yards and 3 touchdowns, while Shaun Terry II has 4 receptions.

The Missouri Tigers’ ground game is averaging 205 yards per contest, and Jamal Roberts leads the way with 47 yards and 1 touchdown. Defensively, Missouri is allowing 14 points and 198 yards per game. Jeremiah Beasley leads the Missouri Tigers with 7 tackles, Jason Dowell has 1 sack, and CJ Bass III has 1 pass deflection.

Kansas Jayhawks Betting Preview

The Kansas Jayhawks beat Long Island University, and they play Arizona State next. Kansas looks for its fourth 2-0 start in the last five seasons. Isaiah Marshall is completing 73.7 percent of his passes for 246 yards, 2 touchdowns, and 0 interceptions. Nik McMillan and Bryson Hayes have combined for 186 receiving yards and 1 touchdown, while Nahzae Cox has 1 reception.

The Kansas Jayhawks’ ground game is averaging 277 yards per contest, and Yasin Willis leads the way with 72 yards and 2 touchdowns. Defensively, Kansas is allowing 6 points and 146 yards per game. Quincy Davis leads the Kansas Jayhawks with 5 tackles, Bam Crouch has 1 sack, and Trey Lathan has 1 sack.

Why the Kansas Jayhawks will win

  • Kansas has won each of its last eight games against non-conference opponents at David Booth Kansas Memorial Stadium.
  • Missouri has lost four of its last five games as an AP-ranked team.
  • The team ranked 23rd in the AP Poll has failed to cover the spread in eight of its last nine games.
  • Kansas has covered the spread in five of its last six games as a home underdog.
  • Kansas has won the first half in each of its last 10 home games against non-conference opponents.
  • Kansas has won the first quarter in each of its last six home games against non-conference opponents.

Why the Missouri Tigers will win

  • Missouri has won each of its last 25 games against non-AP-ranked teams.
  • Kansas has lost eight of its last nine September games as a home underdog.
  • Missouri has covered the spread in each of its last eight road games against non-AP-ranked teams.
  • Kansas has failed to cover the spread in each of its last four games against teams from Missouri.
  • Kansas has lost the first half in eight of its last nine September games as a home underdog.
  • The team ranked 23rd in the AP Poll has won the first quarter in each of its last four games.

Total Points Facts

  • Each of Kansas’ last seven September games as a home underdog have gone OVER the total points line.
  • Each of Missouri’s last four road games have gone UNDER the total points line.

Kansas Jayhawks Player Prop Facts

  • Nik McMillan has recorded 100+ receiving yards in seven consecutive games- the longest streak in the FBS, heading into Week 2.

Missouri Tigers Player Prop Facts

  • Heading into Week 2, Brett Norfleet ranks T1st amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

  • Kansas ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
  • Kansas ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
  • Missouri ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
  • Missouri ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).

Kansas vs Missouri Prediction

Weekday night games can be tricky for visiting teams, and underdogs have a lot of success in these spots. Neither Missouri nor Kansas are fans of each other, and I like my dogs in rivalry spots. Missouri has a young quarterback who doesn’t have road experience, and the Tigers could be down their star running back Ahmad Hardy. Lawrence is going to be rocking for this one, and Kansas should have a shot to spring an upset. This should be a highly contested game. Give me the points with the Jayhawks.

Randy Chambers's Free Pick: Kansas Jayhawks 5.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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