College Football

Louisiana vs Southern Miss Prediction Football Picks Today 10/24/26

Louisiana Ragin' Cajuns (5-2) vs. Southern Mississippi Golden Eagles (1-5)
October 24, 2026 5:00 pm EDT
The Line: Southern Mississippi Golden Eagles 300 / Louisiana Ragin' Cajuns -380; Over/Under: 52.5
(Get latest betting odds)

In this article, we will formulate a Louisiana vs Southern Miss Prediction for this College Football Week 8 matchup on Saturday, October 24th. Let’s take a look at the prediction for this College Football matchup.

Southern Miss Golden Eagles Preview

Southern Miss has a 1-5 record and a 0-2 record in the Sun Belt. They are coming off a 13-23 home loss against Arkansas State and will face ULM and James Madison next .

Offensively, Southern Miss averages 24.2 points per game, ranking 93rd in the nation, while defensively, they allow 32.7 points per game, which is 125th. Southern Miss averages 394.5 total yards per game (260.8 passing and 133.7 rushing), while allowing 447.2 total yards per game (252 rushing and 195.2 passing).

Landry Lyddy leads Southern Miss with 1,032 passing yards with 60.6% completed passes and 7 touchdowns. Steven Robinson leads the team in rushing yards with 432, while Mario Sanders II has a team-high 492 receiving yards and 34 receptions. Defensively, Mathias Haygood has a team-high 55 total tackles (21 of them solo), while Jameer Lewis leads the team with 3 sacks.

Louisiana Ragin’ Cajuns Preview

Louisiana has a 5-2 record and a 2-1 record in the Sun Belt. They are coming off a 33-6 home win against Troy and will face South Alabama and ULM next .

Offensively, Louisiana averages 30 points per game, ranking 66th in the nation, while defensively, they allow 19.3 points per game, which is 35th. Louisiana averages 377.9 total yards per game (177.6 passing and 200.3 rushing), while allowing 298.3 total yards per game (104.3 rushing and 194 passing).

Lunch Winfield leads Louisiana with 1,153 passing yards with 70.1% completed passes and 4 touchdowns and a team-high 463 rushing yards, while KeDarius Wade has a team-high 226 receiving yards and 11 receptions. Defensively, Jake St. Andre has a team-high 49 total tackles (24 of them solo), while Lester Jones leads the team with 2 sacks.

Louisiana Ragin’ Cajuns @ Southern Miss Golden Eagles Betting Trends: Week 8

 

Why the Southern Miss Golden Eagles will win

  • The home team has won each of Louisiana’s last three games.
  • Louisiana has lost each of its last three road games in October.
  • Southern Miss has covered the spread in seven of its last eight home games against teams from Louisiana.
  • Louisiana has failed to cover the spread in five of its last six October games as a road favorite.
  • Louisiana has lost the first half in four of its last five games in October.
  • The home team has won the first quarter in three of the last four games between Louisiana and Southern Miss.

Why the Louisiana Ragin’ Cajuns will win

  • Southern Miss has lost 20 of its last 21 games as an underdog.
  • The favorite has won each of Louisiana’s last seven games.
  • Southern Miss has failed to cover the spread in each of its last six games against conference opponents.
  • Louisiana has covered the spread in seven of its last eight road games against conference opponents.
  • Southern Miss has lost the first half in 13 of its last 14 games as an underdog in Mississippi.
  • The favorite has won the first quarter in each of Southern Miss’ last seven games.

Total Points Facts

  • Each of Louisiana’s last six games as a favorite have gone UNDER the total points line.
  • Four of Southern Miss’ last five home games against teams from Louisiana have gone UNDER the total points line.

Southern Miss Golden Eagles Player Prop Facts

  • Heading into Week 8, Mario Sanders II leads the Sun Belt Conference for receiving yards (492) this season.

Louisiana Ragin’ Cajuns Player Prop Facts

  • Heading into Week 8, Brent Gordon Jr. leads the Sun Belt Conference for forced fumbles (3) this season.

Matchup/League Facts

  • Southern Miss ranks 138th among FBS teams for average point differential in first quarters this season (-9.0).
  • Southern Miss has lost the first quarter in each of its last five games – equal-longest active streak in the FBS.
  • Louisiana ranks 2nd among FBS teams for Q1 opponent points per game this season (1.0).
  • Louisiana ranks 5th among FBS teams for red zone percentage this season (96.3).

Louisiana vs Southern Miss Prediction

In this Louisiana vs Southern Miss prediction, Louisiana is coming as -9.5 road favorites. Both teams have been in opposite trajectories this season, as Southern Miss has won only once and is 1-4 ATS in its last 5, while on the other hand, Louisiana is 5-1 in its last 6 games and 6-1 ATS this season. On top of that, Louisiana has been superior both offensively and defensively, with a +10.7 point differential, while Southern Miss has a bottom-15 defense in the entire country. Take Louisiana and lay the -9.5 points on the road in this one.

Nikos Lagouretos's Free Pick: Louisiana -9.5

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