LSU vs Oklahoma Prediction Football Picks Today 11/29/25
LSU Tigers (7-4) vs. Oklahoma Sooners (9-2)
November 29, 2025 3:30 pm EDT
The Line: Oklahoma Sooners -425 / LSU Tigers 330; Over/Under: 36.5
(Get latest betting odds)
In this article, we will formulate an LSU vs Oklahoma Prediction for this College Football Week 14 game on Saturday, November 29th. Let’s take a look at the prediction for this College Football matchup.
Oklahoma Sooners Preview
Oklahoma has a 9-2 record this season and is sitting 6th in the SEC. They are coming off a 17-6 home win against Missouri. Offensively, Oklahoma averages 27.3 points per game, ranking 72nd in the nation, while defensively, they allow 14 points per game, which is 6th. Oklahoma averages 350.1 total yards per game (221.9 passing and 128.2 rushing), while allowing 280.5 total yards per game (81.1 rushing and 199.4 passing).
John Mateer leads Oklahoma with 2,260 passing yards with 62.3% completed passes and 10 touchdowns. Xavier Robinson leads the team in rushing yards with 408, while Isaiah Sategna has a team-high 56 receptions for 827 receiving yards. Defensively, Kip Lews has a team-high 68 total tackles (34 of them solo), while R Mason Thomas leads the team in sacks, with 6.5, and Eli Bowen leads the team with 2 interceptions.
LSU Tigers Preview
LSU has a 6-4 record this season and is sitting 10th in the SEC. They are coming off a 13-10 home win against Western Kentucky. Offensively, LSU averages 22.6 points per game, ranking 106th in the nation, while defensively, they allow 18.5 points per game, which is 16th. LSU averages 344.9 total yards per game (236.7 passing and 108.2 rushing), while allowing 313.0 total yards per game (121 rushing and 192.0 passing).
Garrett Nussmeier leads LSU with 1,927 passing yards with 67.4% completed passes and 12 touchdowns. Caden Durham leads the team in rushing yards with 463, while Aaron Anderson has a team-high 33 receptions for 398 receiving yards. Defensively, A.J. Haulcy has a team-high 81 total tackles (46 of them solo), while Harold Perkins leads the team in sacks, with 4.0.
LSU Tigers @ Oklahoma Sooners Betting Trends: Week 14
Why the Oklahoma Sooners will win
- Oklahoma has won 19 of its last 20 home games in November.
- LSU has lost each of its last five road games against conference opponents.
- Oklahoma has covered the spread in each of its last six home games in November.
- LSU has failed to cover the spread in seven of its last eight games.
- Oklahoma has won the first half in five of its last six games against conference opponents.
Why the LSU Tigers will win
- The underdog has won three of Oklahoma’s last four games.
- The road team has covered the spread in four of Oklahoma’s last five games.
- Oklahoma has failed to cover the spread in six of its last eight games against non-AP-ranked teams.
Total Points Facts
- Each of Oklahoma’s last seven games against teams from Louisiana have gone OVER the total points line.
- Six of LSU’s last seven games in November have gone UNDER the total points line.
Oklahoma Sooners Player Prop Facts
- Heading into Week 14, Tate Sandell ranks T2nd amongst FBS players for made field goals (22) this season.
LSU Tigers Player Prop Facts
- Heading into Week 14, Damian Ramos ranks T2nd amongst FBS players for made field goals (22) this season.
Matchup/League Facts
- Oklahoma ranks T1st among FBS teams for red zone percentage this season (100.0).
- Oklahoma ranks 3rd among FBS teams for rushing yards allowed per game this season (81.1).
- LSU has recorded the equal-most home wins by a margin of 10 points or less of any FBS team this season (4).
- LSU has lost the first quarter in each of its last six games – longest active streak in the FBS.
LSU vs Oklahoma Prediction
In this LSU vs Oklahoma Prediction, Oklahoma is coming as -10-point home favorites. Oklahoma has been the better team this season, with a better overall record and very strong home presence. They are also been in very good form lately, with a 4-1 record in their last 5 games, while on the other hand, LSU is just 2-3 in its last 5 games and has been terrible against the spread, with a 1-7 record in its last 8 games. Oklahoma has been better both offensively and defensively, with a +13.3 point differential, having the 6th-best defense in the country. I expect the hosts to get the job done in this one, so take Oklahoma and lay the -10 points at home.
