South Carolina Gamecocks (3-2) vs. LSU Tigers (4-1)
October 11, 2025 7:45 pm EDT
The Line: LSU Tigers -8.5 / South Carolina Gamecocks 8.5; Over/Under: 44.5
(Get latest betting odds)
The South Carolina Gamecocks and LSU Tigers meet Saturday in college football action at Tiger Stadium. Here’s a LSU vs South Carolina Prediction. This article will include a LSU vs South Carolina Pick.
South Carolina Gamecocks Betting Preview
The South Carolina Gamecocks lost to Missouri, beat Kentucky, and will play Oklahoma next. The South Carolina Gamecocks have won 9 of their last 12 games. LaNorris Sellers is completing 66.7 percent of his passes for 886 yards, 4 touchdowns, and 1 interception. Vandrevius Jacobs and Nyck Harbor have combined for 543 receiving yards and 3 touchdowns, while Donovan Murph has 5 receptions.
The South Carolina Gamecocks ground game is averaging 99.8 yards per contest, and Rahsul Faison leads the way with 163 yards and 3 touchdowns. Defensively, South Carolina is allowing 18.8 points and 323.4 yards per game. Fred Johnson leads the South Carolina Gamecocks with 25 tackles, Dylan Stewart has 3.5 sacks and Gerald Kilgore has 2 interceptions.
LSU Tigers Betting Preview
The LSU Tigers beat SE Louisiana, lost to Oklahoma, and they play Vanderbilt next. LSU has won 7 of its last 8 games. Garrett Nussmeier is completing 67.3 percent of his passes for 1,159 yards, 7 touchdowns, and 3 interceptions. Barion Brown and Aaron Anderson have combined for 544 receiving yards and 1 touchdown, while Bauer Sharp has 15 receptions.
The LSU Tigers ground game is averaging 104.8 yards per contest, and Caden Durham leads the way with 213 yards and 2 touchdowns. Defensively, LSU is allowing 12.2 points and 293 yards per game. Whit Weeks leads the LSU Tigers with 31 tackles, Damien Shanklin has 2 sacks and Dashawn Spears has 2 interceptions.
Why the LSU Tigers will win
- LSU has won each of its last 20 games against non-AP-ranked teams at Tiger Stadium.
- South Carolina has lost six of its last seven games in October.
- LSU has covered the spread in each of its last eight October home games against non-AP-ranked teams.
- South Carolina has failed to cover the spread in three of its last four games against teams from Louisiana.
- LSU has won the first half in each of its last three home games against conference opponents.
Why the South Carolina Gamecocks will win
- South Carolina has won nine of its last 12 games.
- South Carolina has covered the spread in each of its last 10 road games against top-15 AP-ranked teams.
- LSU has failed to cover the spread in three of its last four games.
- South Carolina has won the first half in four of its last five games against conference opponents.
Total Points Facts
- Each of LSU’s last five games as a favorite against teams from South Carolina have gone OVER the total points line.
- Six of South Carolina’s last eight games against conference opponents have gone OVER the total points line.
LSU Tigers Player Prop Facts
- Heading into Week 7, Dashawn Spears leads the Southeastern Conference for interceptions (2) this season.
South Carolina Gamecocks Player Prop Facts
- Heading into Week 7, Gerald Kilgore leads the Southeastern Conference for interceptions (2) this season.
Matchup/League Facts
- LSU ranks T5th among FBS teams for 4th down conversion percentage this season (83.3).
- LSU ranks T6th among FBS teams for points allowed per game this season (12.2).
- South Carolina ranks 133rd among FBS teams for time of possession per game this season (26:12).
- South Carolina ranks 5th among FBS teams for 4th down conversion percentage against this season (20.0).
LSU vs South Carolina Prediction
LSU is going to get the benefit of the doubt because it’s at home, and it’s a night game. One of the toughest spots in all of college football. However, LSU has been underwhelming offensively, and it’s 1-6 ATS in its last 7 games when favorites of 7 or more points.
South Carolina has had an extra week to prepare and this feels like a spot where it gets to regroup, and we finally see the real Sellers at quarterback. Sellers was a Heisman candidate entering the season. We haven’t seen that yet. I haven’t given up hope. If he does what he’s capable of doing, South Carolina can hang, if not steal this one outright. Give me the points.
