Louisville Cardinals (4-1) vs. Miami (FL) Hurricanes (5-0)
October 17, 2025 7:00 pm EDT
The Line: Miami (FL) Hurricanes -13 / Louisville Cardinals 3; Over/Under: 53.5
(Get latest betting odds)
The Louisville Cardinals and Miami Hurricanes meet Friday in college football action at Hard Rock Stadium. Here’s a Miami vs Louisville Prediction. This article will include a Miami vs Louisville Pick.
Louisville Cardinals Betting Preview
The Louisville Cardinals beat Pitt, lost to Virginia, and they play Boston College next. Louisville has won 7 of its last 8 games. Miller Moss is completing 67 percent of his passes for 1,358 yards, 7 touchdowns, and 4 interceptions. Chris Bell and Caullin Lacy have combined for 789 receiving yards and 4 touchdowns, while Jaleel Skinner has 12 receptions.
The Louisville Cardinals ground game is averaging 115 yards per contest, and Isaac Brown leads the way with 334 yards and 3 touchdowns. Defensively, Louisville is allowing 21 points and 262 yards per game. D’Angelo Hutchinson leads the Louisville Cardinals with 32 tackles, Clev Lubin has 4 sacks and TJ Quinn has 2 interceptions.
Miami Hurricanes Betting Preview
The Miami Hurricanes beat Florida and Florida State, and they play Stanford next. The Miami Hurricanes have won 15 of their last 18 games. Carson Beck is completing 73.4 percent of his passes for 1,213 yards, 11 touchdowns, and 3 interceptions. Malachi Toney and CJ Daniels have combined for 644 receiving yards and 8 touchdowns, while Keelan Marion has 11 receptions.
The Miami Hurricanes ground game is averaging 163.8 yards per contest, and Mark Fletcher Jr. leads the way with 428 yards and 5 touchdowns. Defensively, Miami is allowing 13.6 points and 276.4 yards per game. Rueben Bain Jr. leads the Miami Hurricanes with 26 tackles, Akheem Mesidor has 3.5 sacks and Bryce Fitzgerald has 3 interceptions.
Miami Hurricanes Player Prop Facts
- Heading into Week 8, Bryce Fitzgerald ranks T6th amongst FBS players for interceptions (3) this season.
Louisville Cardinals Player Prop Facts
- Chris Bell has recorded 50+ receiving yards in nine consecutive games – equal-longest streak in the FBS, heading into Week 8.
Matchup/League Facts
- Miami (FL) has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
- Miami (FL) ranks 3rd among FBS teams for H1 opponent points per game this season (3.8).
- Louisville ranks 3rd among FBS teams for 1st downs against this season (71).
- Louisville ranks 8th among FBS teams for passing yards allowed per game this season (150.4).
Miami vs Louisville Prediction
Louisville is tough defensively, but it also hasn’t had the toughest schedule up to this point and I question where the offense is going to come from with a lack of ground game, especially when the competition picks up. Miami is a solid team across the board that’s tough in the trenches and unless a team is willing to match that physicality it could get ugly.
Louisville is 1-4 ATS on the season, while Miami is 4-1 ATS on the season. Louisville is also 3-7 ATS in its last 10 games as a double-digit underdog. At home, this is a spot where Miami should pull away in the second half. I’ll lay the points, as we’re getting this line just under a full 14 points.
