Michigan vs Iowa Prediction Football Picks Today 9/26/26
Iowa Hawkeyes (3-0) vs. Michigan Wolverines (3-0)
September 26, 2026 3:30 pm EDT
The Line: Michigan Wolverines -218 / Iowa Hawkeyes 180; Over/Under: 38.5
(Get latest betting odds)
In this article we will formulate a Michigan vs Iowa prediction for this College Football game on Saturday, September 26th at Michigan Stadium in Ann Arbor, Michigan. Let’s take a look at the prediction for this Week 4 matchup.
Michigan Wolverines Betting Preview
The Michigan Wolverines are 3-0 (0-0) this season after they defeated UTEP by a score of 52-17 last week. Michigan led 17-14 at halftime and they scored 35 points in the second half to get the win and cover. The Wolverines out gained UTEP by a total of 431-150, went 9-13 on third downs, and lost the turnover battle by a total of 2-1 in the game. Bryce Underwood threw for 223 yards and two touchdowns, while Andrew Marsh caught 10 passes for 105 yards and one score. Savion Hiter rushed 11 times for 62 yards and two touchdowns in the win.
Prior to that game, Michigan defeated Oklahoma by a score of 17-10 and Western Michigan by a score of 13-12. The Wolverines have scored 27.3 points per game with 175.7 passing yards and 147.7 rushing yards per game, while they have allowed 13.0 points against per game this season. Bryce Underwood has thrown for 504 yards with three touchdowns and one interception this season.
Iowa Hawkeyes Betting Preview
The Iowa Hawkeyes are 3-0 (0-0) this year after they defeated Northern Iowa by a score of 55-0 in their last game. Iowa led 42-0 at halftime and they cruised to the blowout win in the second half. The Hawkeyes out gained UNI by a total of 640-155, went 3-8 on third downs, and won the turnover battle by a total of 2-0 in the game. Hank Brown threw for 153 yards and two touchdowns, while Nathan McNeil caught three passes for 37 yards. Xavier Williams rushed six times for 151 yards and three scores in the game.
Prior to that win, Iowa defeated Iowa State by a score of 16-13 and NIU by a score of 40-0. The Hawkeyes have scored 37.0 points per game with 209.0 passing yards and 268.0 rushing yards per game, while they have allowed 4.3 points against per game this season. Hank Brown has thrown for 473 yards with three touchdowns and zero interceptions, while Kamari Moulton has rushed 26 times for 240 yards and two scores this year.
Why the Michigan Wolverines will win
- Michigan has won 33 of its last 34 home games in September.
- Iowa has lost 13 of its last 14 games against AP-ranked teams.
- Iowa has failed to cover the spread in each of its last six games as an AP-ranked team against an AP-ranked team.
- Michigan has covered the spread in each of its last four games against Iowa.
- Michigan has won the first quarter in each of its last five games against Iowa.
- Michigan has won the first half in each of its last 18 September games as a home favorite.
Why the Iowa Hawkeyes will win
- Iowa has won each of its last six games.
- Michigan has lost each of its last four games as an AP-ranked team against an AP-ranked team.
- Iowa has covered the spread in each of its last five road games against conference opponents.
- Michigan has failed to cover the spread in each of its last four games as an AP-ranked team against an AP-ranked team.
- Iowa has won the first half in six of its last seven games.
- The underdog has won the first quarter in four of Michigan’s last five games.
Total Points Facts
- Each of Iowa’s last five September games against AP-ranked teams have gone UNDER the total points line.
- Each of Michigan’s last four home games against conference opponents have gone UNDER the total points line.
Michigan Wolverines Player Prop Facts
- Heading into Week 4, John Henry Daley ranks T3rd in the Big Ten Conference for sacks (2.5) this season.
Iowa Hawkeyes Player Prop Facts
- Heading into Week 4, Kamari Moulton ranks 5th amongst qualified players for Yards Per Carry (9.2) this season.
Matchup/League Facts
- Michigan has recorded the equal-most home wins by a margin of 10 points or less of any FBS team this season (2).
- Michigan has recorded the equal-most home wins by a margin of five points or less of any FBS team this season (1).
- Iowa ranks 1st among FBS teams for points allowed per game this season (4.3).
- Iowa has recorded the equal-most home wins by a margin of 40+ points of any FBS team this season (2).
Michigan vs Iowa Prediction
Michigan comes into this matchup with an undefeated record and they are at home, but they have been very inconsistent this year. The Wolverines played six bad quarters against Western Michigan and UTEP, but they played great against a ranked Oklahoma team. Iowa has beaten up on two bad teams, but barely got by a rebuilding Iowa State. Both of these defenses are very good, but I think Michigan has the edge at home. The Wolverines need Underwood to protect the ball, but I think their defense is the best unit on the field.