Michigan vs Purdue Prediction Football Picks Today 11/1/25

The Purdue Boilermakers and Michigan Wolverines meet Saturday in college football action at Michigan Stadium. Here’s a Michigan vs Purdue Prediction. This article will include a Michigan vs Purdue Pick.

Purdue Boilermakers Betting Preview

The Purdue Boilermakers lost to Rutgers and Northwestern, and they play Ohio State next. The Purdue Boilermakers have lost 6 straight games. Ryan Browne is completing 59.5 percent of his passes for 1,689 yards, 8 touchdowns, and 7 interceptions. Nitro Tuggle and Michael Jackson III have combined for 708 receiving yards and 5 touchdowns, while Corey Smith has 14 receptions.

The Purdue Boilermakers ground game is averaging 141.6 yards per contest, and Devin Mockobee leads the way with 521 yards and 4 touchdowns. Defensively, Purdue is allowing 27.8 points and 394.6 yards per game. Mani Powell leads the Purdue Boilermakers with 76 tackles, CJ Nunnally IV has 5 sacks and Myles Slusher has 1 interception.

Michigan Wolverines Betting Preview

The Michigan Wolverines beat Washington and Michigan State, and they play Northwestern next. Michigan has won 5 of its last 6 games. Bryce Underwood is completing 61.1 percent of his passes for 1,526 yards, 7 touchdowns, and 2 interceptions. Donaven McCulley and Andrew Marsh have combined for 729 receiving yards and 4 touchdowns, while Semaj Morgan has 19 receptions.

The Michigan Wolverines ground game is averaging 220.1 yards per contest, and Justice Haynes leads the way with 857 yards and 10 touchdowns. Defensively, Michigan is allowing 17.4 points and 307.5 yards per game. Ernest Hausmann leads the Michigan Wolverines with 55 tackles, Derrick Moore has 6.5 sacks and Cole Sullivan has 3 interceptions.

Why the Michigan Wolverines will win

• Michigan has won each of its last 28 games against non-AP-ranked teams at Michigan Stadium.
• Purdue has lost each of its last 14 games against conference opponents.
• Purdue has failed to cover the spread in each of its last six games against AP-ranked teams.
• Michigan has covered the spread in four of its last five games in November.
• Michigan has won the first half in 18 of its last 20 games against conference opponents at Michigan Stadium.

Why the Purdue Boilermakers will win

• The team ranked 21st in the AP Poll has failed to cover the spread in four of its last five games.
• Purdue has covered the spread in six of its last eight games as an underdog against teams from Michigan.
• Purdue has won the first quarter in three of its last four games against conference opponents.

Total Points Facts

• Each of Purdue’s last four games against AP-ranked teams have gone OVER the total points line.
• Eight of Michigan’s last 10 games in Michigan have gone OVER the total points line.

Michigan Wolverines Player Prop Facts

• Heading into Week 10, Justice Haynes leads the Big Ten Conference for rushing yards (857) this season.

Purdue Boilermakers Player Prop Facts

• Heading into Week 10, Mani Powell leads the Big Ten Conference for tackles (71) this season.

Matchup/League Facts

• Michigan ranks T135th among FBS teams for 4th down conversion percentage this season (20.0).
• Michigan ranks T8th among FBS teams for interceptions this season (11).
• Purdue ranks 128th among FBS teams for Q2 opponent points per game this season (11.5).
• Purdue ranks 127th among FBS teams for average point differential in second quarters this season (-4.9).

Michigan vs Purdue Prediction

Michigan is 3-8 ATS in its last 11 games as a double-digit favorite, so I did consider grabbing the points. However, Purdue is an awful team on both sides of the ball and Michigan looks like a team that’s finding its groove. Michigan runs the ball well and stops the run, and that should be good enough to beat a bad team. Purdue is also 2-5-1 ATS on the season, so this team has little betting value overall. This should be a comfortable win for the Wolverines. I’ll lay the points.