College Football

Mississippi State vs Ole Miss Prediction Football Picks Today 11/28/25

Ole Miss Rebels (10-1) vs. Mississippi State Bulldogs (5-6)
November 28, 2025 12:00 pm EDT
The Line: Mississippi State Bulldogs +7 / Ole Miss Rebels -7; Over/Under: 63.5
(Get latest betting odds)

The Ole Miss Rebels and the Mississippi State Bulldogs meet in week 14 college football action from Davis Wade Stadium on Friday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Ole Miss Rebels vs. Mississippi State Bulldogs prediction.

Ole Miss Rebels Recap

The Ole Miss Rebels come into this game looking to add on to their 34-24 win over Florida last time out to sit at 10-1 on the year. 

Rebels Looking For Comfortable Win For Playoff Hopes

Trinidad Chambliss has thrown for 2,657 yards, 14 touchdowns and 3 interceptions on 65.2% passing while Austin Simmons has 680 passing yards, 4 touchdowns and 5 interceptions on 58.6% passing. Kewan Lacy has a team-high 1,136 rushing yards and 19 touchdowns while Harrison Wallace III has a team-high 647 receiving yards and 2 touchdowns. Dae’Quan Wright has 28 grabs for 485 yards and 4 touchdowns while Deuce Alexander has 32 catches for 483 yards. De’Zhaun Stribling has 467 receiving yards and 3 TDs while Cayden Lee has 460 receiving yards and 3 touchdowns. On defense, TJ Dottery has a team-high 68 total tackles while Princewill Umanmielen has a team-high 5.5 sacks. As a unit, Ole Miss has combined for 22 sacks and 6 interceptions so far this season.

Why the Ole Miss Rebels will win

  • Mississippi State has lost each of its last 12 home games against conference opponents.
  • Ole Miss has won each of its last 11 games in Mississippi.
  • Mississippi State has failed to cover the spread in each of its last six home games against top-10 AP-ranked teams.
  • The road team has covered the spread in eight of the last 10 games between Ole Miss and Mississippi State.

Mississippi State Bulldogs Recap

The Mississippi State Bulldogs come into this game looking to bounce back from a 49-27 loss at the hands of Missouri last time out to sit at 5-6 this season.

Bulldogs Drop Back-To-Back Games

Blake Shapen has thrown for 2,433 yards, 15 touchdowns and 8 interceptions on 64.4% passing while Fluff Bothwell leads the Bulldogs in rushing with 559 yards on the ground and 6 touchdowns and Davon Booth has 547 rushing yards and 7 touchdowns as well this season. Brenen Thompson has 47 receptions for 868 receiving yards and 6 touchdowns while Anthony Evans III has a team-high 63 catches for 751 yards and 4 touchdowns this season. Seydou Traore has 30 catches for 291 yards and 5 TDs while three more Bulldogs have 150+ receiving yards as well this season. On defense, Jahron Manning has a team-high 76 total tackles while Nic Mitchell has a team-high 2.5 sacks. Brylan Lanier has a team-high 3 interceptions as well this season. As a unit, Mississippi State has combined for 20 sacks and 12 interceptions so far this season.

Why the Mississippi State Bulldogs will win

  • The home team has won eight of Ole Miss’ last nine games.
  • Mississippi State has covered the spread in seven of its last eight games in Mississippi.
  • Ole Miss has failed to cover the spread in 10 of its last 12 November games as a favorite.

Total Points Facts

  • Each of the last eight games between Ole Miss and Mississippi State have gone UNDER the total points line.
  • Each of Ole Miss’ last five games as a favorite against Mississippi State have gone UNDER the total points line.

Ole Miss Rebels vs. Mississippi State Bulldogs Prediction

I’m on the Bulldogs and the points here. The Rebels are still going for a playoff spot, but the Bulldogs’ season is on the line here with a bowl game at stake and after a 2-win season last year, a bowl game would mean everything to the Bulldogs. Add in the fact that this is a rivalry game at home, and I think you have to take the free points with Mississippi State.

Chris Ruffolo's Free Pick: Mississippi State Bulldogs +7

Need More? Get Premium Picks

Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

Related Articles

Back to top button