College Football

NC State vs Virginia Tech Prediction Football Picks Today 9/27/25

Virginia Tech Hokies (1-3) vs. NC State Wolfpack (3-1)
September 27, 2025 7:00 pm EDT
The Line: NC State Wolfpack -10 / Virginia Tech Hokies +10; Over/Under: 57.5
(Get latest betting odds)

The Virginia Tech Hokies and the NC State Wolfpack meet in week 5 college football action from Carter-Finley Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Virginia Tech Hokies vs. NC State Wolfpack prediction.

Virginia Tech Hokies Recap

The Virginia Tech Hokies come into this game looking to add on to their 38-6 win over Wofford last time out to sit at 1-3 this season. After this game, the Hokies will head home for a game against Wake Forest.

Hokies Finally Nab First Win

Kyron Drones has thrown for 928 yards, 6 touchdowns and 3 interceptions on 63% passing while also rushing for 144 yards and 4 touchdowns. Marcellous Hawkins has a team-high 187 rushing yards while Donavon Greene has a team-high 203 receiving yards and 2 touchdowns while Ayden Greene has 12 receptions for 200 yards and a touchdown as well this season. On defense, Caleb Woodson has a team-high 24 total tackles while Kelvin Gilliam Jr. has a pair of sacks. As a unit, Virginia Tech’s defense has combined for 8 sacks and a pair of interceptions so far this season. 

Why the Virginia Tech Hokies will win

  • NC State has failed to cover the spread in six of its last seven September games at Carter-Finley Stadium.
  • The road team has covered the spread in each of Virginia Tech’s last three games.

NC State Wolfpack Recap

The NC State Wolfpack come into this game looking to bounce back from a 45-33 loss at the hands of Duke last time out to slip to 3-1 this season. After this game, the Wolfpack will take on Campbell at home.

Wolfpack Coming Off Of First Loss

CJ Bailey has thrown for 1,083 yards, 7 touchdowns and 4 interceptions on 71.9% passing while Hollywood Smothers has a team-high 503 rushing yards and 4 touchdowns to lead the Wolfpack in rushing. Terrell Anderson leads NC State with 273 receiving yards along with 15 receptions and a pair of touchdowns while Wesley Grimes has 173 receiving yards and four more NC State receivers have 100 receiving yards as well this season. On defense, Sean Brown has a team-high 39 total tackles including 16 solo tackles while the Wolfpack defense as a whole has combined for 5 sacks and 3 interceptions so far this season. 

Why the NC State Wolfpack will win

  • NC State has won each of its last 10 home games against teams from Virginia.
  • Virginia Tech has lost each of its last seven games in North Carolina.
  • Virginia Tech has failed to cover the spread in nine of its last 10 games in North Carolina.
  • NC State has covered the spread in four of its last five games against conference opponents.

Total Points Facts

  • Seven of NC State’s last eight games against conference opponents have gone OVER the total points line.
  • Six of Virginia Tech’s last seven road games against non-AP-ranked teams have gone OVER the total points line.

Virginia Tech Hokies vs. NC State Wolfpack Prediction

I’m on the over in this one. I get the case to be made for either side, and if I had to pick a side in this game, I’d probably lean towards NC State, but the Wolfpack’s defense or lack thereof, makes me not want to lay double digits with them but I also can’t trust Virginia Tech to keep this game close. I think we get into the 60s in terms of points scored here, so give me the over.

Chris Ruffolo's Free Pick: Over 57.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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