Northern Illinois vs Toledo Prediction 11/5/25 College Football Picks Today
Northern Illinois vs Toledo
November 5, 2025 7:00 pm EDT
The Line: Toledo -14 / Over/Under: 41.5
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In this article, we will formulate a Northern Illinois vs Toledo Prediction for this College Football Week 11 game on Wednesday, November 5th. Let’s take a look at the prediction for this College Football matchup.
Toledo Rockets Preview
Toledo has a 4-4 record this season and is sitting 6th in the MAC. They are 5-3 ATS, 4-4 in Over/Under and have a 4-0 home record and a 0-4 away record. Toledo is coming off a 7-28 road loss against Washington State and will face Miami (OH), Ball State and Central Michigan next.
Offensively, Toledo averages 31.8 points per game, ranking 48th in the nation, while defensively, they allow 16.0 points per game, which is 10th. Toledo averages 436.5 total yards per game (253.3 passing and 183.3 rushing), while allowing 236.3 total yards per game (93.5 rushing and 142.8 passing).
Tucker Gleason leads Toledo with 1,721 passing yards with 64.5% completed passes and 13 touchdowns. Deamonte Trayanum leads the team in rushing yards with 601, while Junior Vandeross III has a team-high 52 receptions for 608 receiving yards. Defensively, K’Von Sherman has a team-high 56 total tackles (33 of them solo), while Malachi Davis leads the team in sacks, with 4.5, and Braden Awls leads the team in interceptions, with 4.
Northern Illinois Huskies Preview
Northern Illinois has a 2-6 record this season and is sitting 11th in the MAC. They are 2-6 ATS, 2-6 in Over/Under and have a 2-2 home record and a 0-4 away record. Northern Illinois is coming off a 21-7 home win against Ball State and will face Massachusetts, Western Michigan and Kent State next.
Offensively, Northern Illinois averages 13.4 points per game, ranking 134th in the nation, while defensively, they allow 22.1 points per game, which is 43rd. Northern Illinois averages 276.1 total yards per game (103.1 passing and 173.0 rushing), while allowing 343.9 total yards per game (176.1 rushing and 167.8 passing).
Josh Holst leads Northern Illinois with 602 passing yards with 62.4% completed passes and 4 touchdowns. Telly Johnson Jr. leads the team in rushing yards with 581, while DeAree Rogers has a team-high 38 receptions for 439 receiving yards. Defensively, Quinton Urwiler has a team-high 97 total tackles (53 of them solo), while Nathan Voorhis leads the team in sacks, with 10.0. Jasper Beeler, Muhammad Jammeh, Donte Harrison and James Finley IV have one interception each.
Northern Illinois Huskies @ Toledo Rockets Betting Trends: Week 11
Toledo Rockets Player Prop Facts
- Heading into Week 11, Junior Vandeross III leads the Mid-American Conference for receiving touchdowns (8) this season.
Northern Illinois Huskies Player Prop Facts
- Heading into Week 11, Telly Johnson Jr. leads the Mid-American Conference for yards per carry (6.0) this season.
Matchup/League Facts
- Toledo has suffered the equal-most road losses by a margin of 10 points or less of any FBS team this season (3).
- Toledo ranks T1st among FBS teams for 1st downs against this season (106).
- Northern Illinois ranks 135th among FBS teams for passing yards per game this season (103.1).
- Northern Illinois ranks 135th among FBS teams for 1st downs this season (111).
Northern Illinois vs Toledo Prediction
In their previous meeting last season, Toledo won 13-6 on the road and is 4-1 in their last 5 meetings against Northern Illinois, but Northern Illinois is 3-2 in its last 5 visits in Toledo. Over is 4-2 in their last 6 meetings.
In this Northern Illinois vs Toledo Prediction, Toledo is coming as -14-point road favorites, with the total set at 41.5 points. Northern Illinois has been terrible this season and is 1-6 in its last 7 games, having lost all of their four road games. On the flip side, Toledo is perfect at home with a 4-0 record, while Northern Illinois is just 2-6 against the spread, having the third-worst offense in the country, going up against Toledo’s 10th-best defense. I expect the hosts to dominate this game, so take Toledo by -14.