Northwestern vs Minnesota Prediction Football Picks Today 11/22/25

In this article we will formulate a Northwestern vs Minnesota prediction for this College Football game on Saturday, November 22nd at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this week 13 matchup. 

Northwestern Wildcats Betting Preview

The Northwestern Wildcats are 5-5 (3-4) this season after they lost to Michigan by a score of 24-22 in their last game. Northwestern trailed 7-6 at halftime and 21-9 in the fourth quarter, but they took a 22-21 lead, before allowing a last second field goal for the loss. The Wildcats were out gained by a total of 496-245, went 2-12 on third downs, and won the turnover battle by a total of 5-0 in the game. Preston Stone went 13-27 for 184 yards, while Caleb Komolafe rushed 12 times for 31 yards and one score. Hunter Welcing led the receivers with four catches for 81 yards in the loss. The NW defense recorded three sacks and five tackles for loss in the game. 

Prior to that game, Northwestern lost to USC by a score of 38-17 and Nebraska by a score of 28-21. The Wildcats have lost three games in a row and they are currently tied for 11th in the Big Ten standings. Northwestern has scored 21.9 points per game with 171.3 passing yards and 169.4 rushing yards per game, while they have allowed 19.6 points against per game this season. Preston Stone has thrown for 1,706 yards, 11 touchdowns, and nine interceptions, while Caleb Komolafe has rushed 153 times for 757 yards and nine scores this season. 

Minnesota Golden Gophers Betting Preview

The Minnesota Golden Gophers are 6-4 (4-3) this year after they lost to Oregon by a score of 42-13 in their last game. Minnesota trailed 28-6 at halftime and they cut the deficit to 28-13 in the second half, but couldn’t get any closer in the loss. The Golden Gophers were out gained by a total of 510-200, went 7-16 on third downs, and won the turnover battle by a total of 1-0 in the game. Drake Lindsey went 19-32 for 138 yards and one touchdown, while Darius Taylor rushed 10 times for 57 yards. Taylor also led the receivers with four catches for 40 yards in the loss. The Minnesota defense recorded one sack and five tackles for loss in the game. 

Prior to that game, Minnesota defeated Michigan State by a score of 23-20, but lost to Iowa by a score of 41-3 before that. The Golden Gophers have lost two of their last three games and they are currently tied for sixth in the Big Ten standings. Minnesota has scored 22.7 points per game with 196.8 passing yards and 105.0 rushing yards per game, while they have allowed 23.6 points against per game this season. Drake Lindsey has thrown for 1,881 yards, 11 touchdowns, and six interceptions, while Darius Taylor has rushed for 411 yards and one score on 90 carries this year. 

Why the Northwestern Wildcats will win

• The home team has won each of Minnesota’s last 10 games.
• Minnesota has lost each of its last four road games.
• Minnesota has failed to cover the spread in seven of its last eight games.
• Northwestern has covered the spread in five of its last six home games.
• Minnesota has lost the first half in nine of its last 11 road games against conference opponents.

Total Points Facts

• Each of Minnesota’s last four games as a road underdog have gone OVER the total points line.
• Each of Northwestern’s last four games in November have gone OVER the total points line.

Matchup/League Facts

• Northwestern ranks 118th among FBS teams for passing yards per game this season (171.3).
• Northwestern ranks 19th among FBS teams for time of possession per game this season (32:08).
• Minnesota ranks 129th among FBS teams for yards per game this season (301.8).
• Minnesota ranks 126th among FBS teams for rushing yards per game this season (105.0).

Northwestern vs Minnesota Prediction

Northwestern comes into this contest looking to snap a three game losing streak, but they nearly upset Michigan last week and will be at home. The Wildcats have played much better at home this season, while Minnesota is 0-4 on the road. The Golden Gophers have allowed 41 and 42 points in their last two road games and their offense has been very low scoring away from home. If this game was at Minnesota, it would be a different story, but take Northwestern to win here. 

David Racey is 128-108 (54%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!