Ohio vs Ohio State Prediction 9/13/25 College Football Picks Today

In this article, we will formulate an Ohio vs Ohio State Prediction for this College Football Week 3 game on Saturday, September 13^th at the Ohio Stadium. Let’s take a look at the prediction for this College Football matchup.

Ohio State Buckeyes Preview

The Buckeyes have a 2-0 record this season and are ranked as No.1 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Buckeyes are coming off a 70-0 home victory over Grambling. California outgained their opponents by 467-192 yards. They had 28/39 completed passes, 286 passing yards, 181 rushing yards, with turnovers being 2-1. The Golden Bears went 6-12 in third down efficiency and had 7-81 penalties.

Jaron-Keawe Sagapolutele had 26/37 passes, a team-high 259 passing yards, no touchdowns and one interception. Kendrick Raphael added a team-high 131 rushing yards, while Mark Hamper caught 1 pass for 14 yards. Defensively, Luke Ferrelli had 11 total tackles, three of them solo, while TJ Bush Jr. and Ryan McCulloch each recorded one sack. Hezekiah Masses had one interception for 28 yards.

Ohio Bobcats Preview

The Bobcats have a 1-1 record this season and are ranked as No.64 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Bobcats are coming off a 17-10 home victory over West Virginia. Ohio State outgained their opponents by 651-166 yards. They had 24/28 completed passes, 377 passing yards, 274 rushing yards, with turnovers being 1-3. The Buckeyes went 5-7 in third down efficiency and had 3-15 penalties.

Julian Sayin had 18/19 passes, a team-high 306 passing yards, four touchdowns and one interception. Bo Jackson added a team-high 45 rushing yards, while Jeremiah Smith caught 5 passes for 119 yards. Defensively, C.J. Hicks had 6 total tackles, two of them solo, while Davison Igbinosun and Carnell Tate each recorded one sack. Caleb Downs had one interception.

Ohio vs Ohio State Prediction

Ohio State has won both meetings against Ohio, with their most recent meeting being back in 2010, where the Buckeyes won 43-7 at home.

In this Ohio vs Ohio State Prediction, Ohio State is coming in as -31-point home favorites, with the total set at 51 points. Both teams are coming off wins in their previous games, but Ohio State has been dominating so far, having won and covered both of their games, while playing elite defense, holding their opponents into just 3.5 points per game. The Buckeyes are projected as the number one team in the nation, and have been looking superb so far. The spread is very big, but for a reason, as the book also expect a blowout victory. Take the Ohio State Buckeyes and lay the -31 points at home.

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